Peptide exchange in MHC molecules

Major histocompatibihty complex (MHC)‐encoded glycoproteins bind peptide antigens through non‐covalent interactions to generate complexes that are displayed on tbe surface of antigen‐presenting cells (APC) for recognition by T ceils, Peptide‐binding site occupancy is necessary for stable assembly of...

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Veröffentlicht in:	Immunological reviews 1999-12, Vol.172 (1), p.229-238
Hauptverfasser:	Jensen, Peter E., Weber, Dominique A., Thayer, Wesley R, Westerman, Larry E., Dao, Chinh T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation Autoimmunity endosomes Histocompatibility Antigens - metabolism Histocompatibility Antigens Class I - metabolism Histocompatibility Antigens Class II HLA-D Antigens - metabolism Humans Hydrogen-Ion Concentration Models, Biological Peptides - immunology Peptides - metabolism
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