Megalin is a receptor for albumin in astrocytes and is required for the synthesis of the neurotrophic factor oleic acid

We have previously shown that the uptake and transcytosis of albumin in astrocytes promote the synthesis of the neurotrophic factor oleic acid. Although the mechanism by which albumin induces oleic acid synthesis is well known, the mechanism of albumin uptake in astrocytes remains unknown. In this w...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neurochemistry 2008-08, Vol.106 (3), p.1149-1159
Hauptverfasser:	Bento-Abreu, André, Velasco, Ana, Polo-Hernández, Erica, Pérez-Reyes, Pedro Luis, Tabernero, Arantxa, Medina, José M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids albumin albumins Animals Animals, Newborn Astrocytes - drug effects Astrocytes - metabolism Binding sites Biochemistry Biological and medical sciences brain Cattle Cells, Cultured Chemical synthesis Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases differentiation Fundamental and applied biological sciences. Psychology glia Isolated neuron and nerve. Neuroglia Low Density Lipoprotein Receptor-Related Protein-2 - deficiency Low Density Lipoprotein Receptor-Related Protein-2 - metabolism Low Density Lipoprotein Receptor-Related Protein-2 - physiology Medical sciences Nerve Growth Factors - biosynthesis Nerve Growth Factors - genetics Neurology neurons oleic acid Oleic Acid - biosynthesis Oleic Acid - genetics Rats Rats, Wistar Receptors, Albumin - genetics Receptors, Albumin - metabolism Receptors, Albumin - physiology Serum Albumin, Bovine - pharmacology siRNA Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!