Interleukine-8 acts as a strong peripheral blood granulocyte-recruiting agent rather than as a hematopoietic progenitor cell-mobilizing factor

Intravenous infusion of Interleukine-8 has been shown to lead to a rapid mobilization of hematopoietic cells in mice and rhesus monkeys. We report in this study that the IL-8-mediated mobilizing effect results in low levels of circulating CD34+ cells, whereas a rapid and strong recruitment of mature...

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Veröffentlicht in:	Journal of hematotherapy & stem cell research 1999-08, Vol.8 (4), p.365-379
Hauptverfasser:	Vetillard, J, Drouet, M, Neildez-Nguyen, T M, Mestries, J C, Mathieu, J, Thierry, D, Herodin, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD34 Blood Cell Count Granulocytes - drug effects Granulocytes - pathology Hematopoietic Stem Cell Mobilization Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - drug effects Hematopoietic Stem Cells - pathology Humans Interleukin-8 - pharmacology Leukocyte Transfusion Male Mice Papio
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