Motor dysfunction in a mouse model for Down syndrome

Motor deficits are among the most frequently occurring features of Down syndrome (DS). Individuals with DS exhibit disturbances in the dynamics of movement production and postural control that are thought to have a significant impact in delaying their acquisition of motor skills. The origin of these...

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Veröffentlicht in:	Physiology & behavior 1999-12, Vol.68 (1), p.211-220
Hauptverfasser:	Costa, Alberto C.S, Walsh, Kathryn, Davisson, Muriel T
Format:	Artikel
Sprache:	eng
Schlagworte:	Aneuploidy Animals Biological and medical sciences Cerebellum - physiopathology Chromosome aberrations Disease Models, Animal Down syndrome Down Syndrome - genetics Down Syndrome - physiopathology Female Hand Strength - physiology Locomotion - physiology Male Maze Learning - physiology Medical genetics Medical sciences Mice Mice, Neurologic Mutants Morris water maze Motor dysfunction Motor Skills - physiology Mouse models Orientation - physiology Postural Balance - physiology Posture - physiology Reaction Time - physiology Space life sciences Trisomy 16 Trisomy 21 Ts65Dn mice
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