Biohybride nerve guide for regeneration: degradable polylactide fibers coated with rat Schwann cells

The restricted capacity of the nervous system to regenerate calls for novel therapeutic concepts. We have tested biocompatible polylactide fibers as potential nerve guides that could bridge proximal nerve stumps and synaptic target regions after nerve lesion. Polylactides have the great advantage th...

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Veröffentlicht in:	Neuroscience letters 1999-12, Vol.277 (3), p.165-168
Hauptverfasser:	Steuer, Heiko, Fadale, Roberto, Müller, Erhard, Müller, Hans-Werner, Planck, Heinrich, Schlosshauer, Burkhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axon Axons - physiology Biocompatible Materials Biological and medical sciences Cell Adhesion - physiology Chick dorsal root ganglia Chick Embryo Development. Senescence. Regeneration. Transplantation Fluorescent Antibody Technique Fundamental and applied biological sciences. Psychology Ganglia, Spinal - physiology Immunofluorescence Microscopy, Electron, Scanning Nerve Regeneration - physiology Neurology - methods Polyesters Polylactide Rats Rats, Wistar Regeneration Scanning electron microscopy Schwann cells Schwann Cells - physiology Sciatic nerve Sciatic Nerve - cytology Sciatic Nerve - physiology Stereoisomerism Vertebrates: nervous system and sense organs
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