The efficiency of in-situ hybridization on human chromosomes with alphoid DNAs is enhanced by previous digestion with AluI and TaqI

Centromeric alphoid DNAs of human chromosomes 6, 9, 16 and Y were employed to obtain information on the molecular mechanism(s) determining cytological effects produced by digestion in situ with AluI and TaqI restriction enzymes, possibly related to the structure of the above-cited areas. The followi...

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Veröffentlicht in:Chromosome research 1999-12, Vol.7 (8), p.593-602
Hauptverfasser: Nieddu, M, Rossino, R, Pichiri, G, Rocchi, M, Setzu, M D, Mezzanotte, R
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Sprache:eng
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