Monitoring Adherence and Defaulting for Antiretroviral Therapy in 5 East African Countries: An Urgent Need for Standards
Objectives: A cross-sectional survey was performed in 24 systems of care providing antiretroviral medications in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda to examine current practices in monitoring rates of treatment adherence and defaulting. Results: Only 20 of 48 facilities reported routinely...
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| Veröffentlicht in: | Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) Ill. : 2002), 2008-07, Vol.7 (4), p.193-199 |
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| container_title | Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) |
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| creator | Chalker, John Andualem, Tenaw Minzi, Omary Ntaganira, Joseph Ojoo, Atieno Waako, Paul Ross-Degnan, Dennis |
| description | Objectives: A cross-sectional survey was performed in 24 systems of care providing antiretroviral medications in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda to examine current practices in monitoring rates of treatment adherence and defaulting.
Results: Only 20 of 48 facilities reported routinely measuring individual patient adherence levels; only 12 measured rates of adherence for the clinic population. The rules for determining which patients were included in the calculation of rates were unclear. Fourteen different definitions of treatment defaulting were in use. Facilities routinely gather potentially useful data, but the frequency of doing so varied widely.
Conclusions: Individual and program treatment adherence and defaulting are not routinely monitored; when done, the operational definitions and methods varied widely, making comparisons across programs unreliable. There is a pressing need to determine which measures are the most feasible and reliable to collect, the most useful for clinical counseling, and most informative for program management. |
| doi_str_mv | 10.1177/1545109708320687 |
| format | Article |
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Results: Only 20 of 48 facilities reported routinely measuring individual patient adherence levels; only 12 measured rates of adherence for the clinic population. The rules for determining which patients were included in the calculation of rates were unclear. Fourteen different definitions of treatment defaulting were in use. Facilities routinely gather potentially useful data, but the frequency of doing so varied widely.
Conclusions: Individual and program treatment adherence and defaulting are not routinely monitored; when done, the operational definitions and methods varied widely, making comparisons across programs unreliable. There is a pressing need to determine which measures are the most feasible and reliable to collect, the most useful for clinical counseling, and most informative for program management.</description><identifier>ISSN: 1545-1097</identifier><identifier>ISSN: 2325-9574</identifier><identifier>EISSN: 1557-0886</identifier><identifier>EISSN: 2325-9582</identifier><identifier>DOI: 10.1177/1545109708320687</identifier><identifier>PMID: 18626124</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adult ; Africa, Eastern ; Anti-HIV Agents - therapeutic use ; Antiretroviral drugs ; Antiretroviral therapy ; Antiviral agents ; Child ; Computation ; Counseling ; Dosage and administration ; Drug therapy ; Health care industry ; Health Care Surveys ; HIV infection ; HIV Infections - drug therapy ; HIV Infections - prevention & control ; HIV Infections - virology ; HIV-1 ; Humans ; Interviews as Topic ; Operational definitions ; Patient Compliance - statistics & numerical data ; Prescription drugs ; Program Evaluation - standards ; Services ; Surveys ; Surveys and Questionnaires ; Treatment compliance ; Treatment Outcome</subject><ispartof>Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002), 2008-07, Vol.7 (4), p.193-199</ispartof><rights>COPYRIGHT 2008 Sage Publications, Inc.</rights><rights>Copyright SAGE PUBLICATIONS, INC. Jul 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3907-dae0c3352a5c438a062abc7f14b43f0fe63307eb07af8f921692bc5403b85baf3</citedby><cites>FETCH-LOGICAL-c3907-dae0c3352a5c438a062abc7f14b43f0fe63307eb07af8f921692bc5403b85baf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1545109708320687$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1545109708320687$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,864,21966,27344,27853,27924,27925,33774,44945,45333</link.rule.ids><linktorsrc>$$Uhttps://journals.sagepub.com/doi/full/10.1177/1545109708320687?utm_source=summon&utm_medium=discovery-provider$$EView_record_in_SAGE_Publications$$FView_record_in_$$GSAGE_Publications</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18626124$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chalker, John</creatorcontrib><creatorcontrib>Andualem, Tenaw</creatorcontrib><creatorcontrib>Minzi, Omary</creatorcontrib><creatorcontrib>Ntaganira, Joseph</creatorcontrib><creatorcontrib>Ojoo, Atieno</creatorcontrib><creatorcontrib>Waako, Paul</creatorcontrib><creatorcontrib>Ross-Degnan, Dennis</creatorcontrib><title>Monitoring Adherence and Defaulting for Antiretroviral Therapy in 5 East African Countries: An Urgent Need for Standards</title><title>Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)</title><addtitle>J Int Assoc Physicians AIDS Care (Chic)</addtitle><description>Objectives: A cross-sectional survey was performed in 24 systems of care providing antiretroviral medications in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda to examine current practices in monitoring rates of treatment adherence and defaulting.
Results: Only 20 of 48 facilities reported routinely measuring individual patient adherence levels; only 12 measured rates of adherence for the clinic population. The rules for determining which patients were included in the calculation of rates were unclear. Fourteen different definitions of treatment defaulting were in use. Facilities routinely gather potentially useful data, but the frequency of doing so varied widely.
Conclusions: Individual and program treatment adherence and defaulting are not routinely monitored; when done, the operational definitions and methods varied widely, making comparisons across programs unreliable. There is a pressing need to determine which measures are the most feasible and reliable to collect, the most useful for clinical counseling, and most informative for program management.</description><subject>Adult</subject><subject>Africa, Eastern</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Antiretroviral drugs</subject><subject>Antiretroviral therapy</subject><subject>Antiviral agents</subject><subject>Child</subject><subject>Computation</subject><subject>Counseling</subject><subject>Dosage and administration</subject><subject>Drug therapy</subject><subject>Health care industry</subject><subject>Health Care Surveys</subject><subject>HIV infection</subject><subject>HIV Infections - drug therapy</subject><subject>HIV Infections - prevention & control</subject><subject>HIV Infections - virology</subject><subject>HIV-1</subject><subject>Humans</subject><subject>Interviews as Topic</subject><subject>Operational definitions</subject><subject>Patient Compliance - statistics & numerical data</subject><subject>Prescription drugs</subject><subject>Program Evaluation - standards</subject><subject>Services</subject><subject>Surveys</subject><subject>Surveys and Questionnaires</subject><subject>Treatment compliance</subject><subject>Treatment Outcome</subject><issn>1545-1097</issn><issn>2325-9574</issn><issn>1557-0886</issn><issn>2325-9582</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>BHHNA</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqFkc1rFTEUxQdR7IfuXUlAcDc138m4G561ClUXtushk7l5psxLnklG7H9vxvegUBDJIiH3d869yWmaVwRfEKLUOyK4ILhTWDOKpVZPmlMihGqx1vLpeuaiXesnzVnOdxgzpRR73pwQLakklJ82v7_E4EtMPmxRP_2ABMECMmFCH8CZZS5rwcWE-lB8gpLiL5_MjG4qavb3yAck0KXJBfUueWsC2sQllOQhv68adJu2EAr6CjD9tfleqrdJU37RPHNmzvDyuJ83tx8vbzaf2utvV583_XVrWYdVOxnAljFBjbCcaYMlNaNVjvCRM4cdSMawghEr47TrKJEdHa3gmI1ajMax8-btwXef4s8Fchl2PluYZxMgLnmQHesIU_S_ICWkfrSQFXzzCLyLSwr1EQNlnHEluWaVujhQWzPD4IOLJRlb1wQ7b2MA5-t9TzThinZ07Y8PAptizgncsE9-Z9L9QPCwpj08TrtKXh8nWcYdTA-CY7wVaA9ANlt4GPOfhn8AiOiwTg</recordid><startdate>200807</startdate><enddate>200807</enddate><creator>Chalker, John</creator><creator>Andualem, Tenaw</creator><creator>Minzi, Omary</creator><creator>Ntaganira, Joseph</creator><creator>Ojoo, Atieno</creator><creator>Waako, Paul</creator><creator>Ross-Degnan, Dennis</creator><general>SAGE Publications</general><general>Sage Publications, Inc</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7U3</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHHNA</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200807</creationdate><title>Monitoring Adherence and Defaulting for Antiretroviral Therapy in 5 East African Countries: An Urgent Need for Standards</title><author>Chalker, John ; Andualem, Tenaw ; Minzi, Omary ; Ntaganira, Joseph ; Ojoo, Atieno ; Waako, Paul ; Ross-Degnan, Dennis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3907-dae0c3352a5c438a062abc7f14b43f0fe63307eb07af8f921692bc5403b85baf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Africa, Eastern</topic><topic>Anti-HIV Agents - therapeutic use</topic><topic>Antiretroviral drugs</topic><topic>Antiretroviral therapy</topic><topic>Antiviral agents</topic><topic>Child</topic><topic>Computation</topic><topic>Counseling</topic><topic>Dosage and administration</topic><topic>Drug therapy</topic><topic>Health care industry</topic><topic>Health Care Surveys</topic><topic>HIV infection</topic><topic>HIV Infections - drug therapy</topic><topic>HIV Infections - prevention & control</topic><topic>HIV Infections - virology</topic><topic>HIV-1</topic><topic>Humans</topic><topic>Interviews as Topic</topic><topic>Operational definitions</topic><topic>Patient Compliance - statistics & numerical data</topic><topic>Prescription drugs</topic><topic>Program Evaluation - standards</topic><topic>Services</topic><topic>Surveys</topic><topic>Surveys and Questionnaires</topic><topic>Treatment compliance</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chalker, John</creatorcontrib><creatorcontrib>Andualem, Tenaw</creatorcontrib><creatorcontrib>Minzi, Omary</creatorcontrib><creatorcontrib>Ntaganira, Joseph</creatorcontrib><creatorcontrib>Ojoo, Atieno</creatorcontrib><creatorcontrib>Waako, Paul</creatorcontrib><creatorcontrib>Ross-Degnan, Dennis</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Social Services Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Sociological Abstracts</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Chalker, John</au><au>Andualem, Tenaw</au><au>Minzi, Omary</au><au>Ntaganira, Joseph</au><au>Ojoo, Atieno</au><au>Waako, Paul</au><au>Ross-Degnan, Dennis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Monitoring Adherence and Defaulting for Antiretroviral Therapy in 5 East African Countries: An Urgent Need for Standards</atitle><jtitle>Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002)</jtitle><addtitle>J Int Assoc Physicians AIDS Care (Chic)</addtitle><date>2008-07</date><risdate>2008</risdate><volume>7</volume><issue>4</issue><spage>193</spage><epage>199</epage><pages>193-199</pages><issn>1545-1097</issn><issn>2325-9574</issn><eissn>1557-0886</eissn><eissn>2325-9582</eissn><abstract>Objectives: A cross-sectional survey was performed in 24 systems of care providing antiretroviral medications in Ethiopia, Kenya, Rwanda, Tanzania, and Uganda to examine current practices in monitoring rates of treatment adherence and defaulting.
Results: Only 20 of 48 facilities reported routinely measuring individual patient adherence levels; only 12 measured rates of adherence for the clinic population. The rules for determining which patients were included in the calculation of rates were unclear. Fourteen different definitions of treatment defaulting were in use. Facilities routinely gather potentially useful data, but the frequency of doing so varied widely.
Conclusions: Individual and program treatment adherence and defaulting are not routinely monitored; when done, the operational definitions and methods varied widely, making comparisons across programs unreliable. There is a pressing need to determine which measures are the most feasible and reliable to collect, the most useful for clinical counseling, and most informative for program management.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>18626124</pmid><doi>10.1177/1545109708320687</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002), 2008-07, Vol.7 (4), p.193-199 |
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| language | eng |
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| source | Sage Journals GOLD Open Access 2024 |
| subjects | Adult Africa, Eastern Anti-HIV Agents - therapeutic use Antiretroviral drugs Antiretroviral therapy Antiviral agents Child Computation Counseling Dosage and administration Drug therapy Health care industry Health Care Surveys HIV infection HIV Infections - drug therapy HIV Infections - prevention & control HIV Infections - virology HIV-1 Humans Interviews as Topic Operational definitions Patient Compliance - statistics & numerical data Prescription drugs Program Evaluation - standards Services Surveys Surveys and Questionnaires Treatment compliance Treatment Outcome |
| title | Monitoring Adherence and Defaulting for Antiretroviral Therapy in 5 East African Countries: An Urgent Need for Standards |
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