Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species

Diesel emission particulates (DEP) exert effects on the immune system and act as an adjuvant which enhances allergic inflammation. Animal and human models have delineated the effects of DEP chemicals in enhancing IgE production and promoting T-helper cell-2 (Th2) differentiation. An important primar...

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Veröffentlicht in:	Annals of allergy, asthma, & immunology asthma, & immunology, 1999-12, Vol.83 (6), p.624-629
Hauptverfasser:	Casillas, Adrian M., Hiura, Tim, Li, Ning, Nel, Andre E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Asthma - etiology Biological and medical sciences Environmental pollutants toxicology Humans hypersensitivity immune system inflammation Medical sciences Reactive Oxygen Species - physiology Toxicology Vehicle Emissions - adverse effects
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