Characterisation of excipient-free nanoporous microparticles (NPMPs) of bendroflumethiazide

The purpose of this study was to prepare excipient-free porous microparticles of bendroflumethiazide by spray drying and to characterise the physicochemical properties of the particles produced. Solutions of bendroflumethiazide in ethanol/water, ethanol/water/ammonium carbonate or methanol/water/amm...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2008-08, Vol.69 (3), p.1182-1186
Hauptverfasser:	Healy, A.M., McDonald, B.F., Tajber, L., Corrigan, O.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amorphous Antihypertensive Agents - administration & dosage Antihypertensive Agents - chemistry Bendroflumethiazide - administration & dosage Bendroflumethiazide - chemistry Biological and medical sciences Desiccation Excipient-free General pharmacology Medical sciences Microscopy, Electron, Scanning Nanoparticles Nanopores Nebulizers and Vaporizers Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Porous microparticles Powders Spectroscopy, Fourier Transform Infrared Spray drying Surface-Active Agents X-Ray Diffraction
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