Entoptic foveal avascular zone measurement and diabetic retinopathy
Entoptic visualization of the foveal avascular zone (FAZ) provides a noninvasive method for measurement of the FAZ. To determine if repeatability of measurement with this technique is good enough to monitor changes in diabetic retinopathy, we quantify (1) the repeatability of entoptic FAZ measuremen...
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| Veröffentlicht in: | Optometry and vision science 1999-12, Vol.76 (12), p.826-831 |
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| container_title | Optometry and vision science |
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| creator | HILMANTEL, G APPLEGATE, R. A VAN HEUVEN, W. A. J STOWERS, S. P BRADLEY, A LEE, R. L |
| description | Entoptic visualization of the foveal avascular zone (FAZ) provides a noninvasive method for measurement of the FAZ. To determine if repeatability of measurement with this technique is good enough to monitor changes in diabetic retinopathy, we quantify (1) the repeatability of entoptic FAZ measurement in healthy subjects and (2) the relationship between measured FAZ diameter and the severity of retinopathy.
(1) To determine FAZ measurement repeatability, 10 healthy adults entoptically measured their FAZ diameters in 11 separate testing sessions. (2) In a separate experiment, 53 patients with varying levels of diabetic retinopathy and 21 control subjects used a vascular entoptoscope to measure their FAZ diameters.
The disease-related increase in FAZ diameter is large (approximately 400 microm) compared to the repeatability of the entoptic measurement within a subject (SD approximately 35 microm).
Entoptic measurements have the repeatability necessary to reliably monitor increases in FAZ diameter of the magnitude of those induced by diabetes. |
| doi_str_mv | 10.1097/00006324-199912000-00017 |
| format | Article |
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(1) To determine FAZ measurement repeatability, 10 healthy adults entoptically measured their FAZ diameters in 11 separate testing sessions. (2) In a separate experiment, 53 patients with varying levels of diabetic retinopathy and 21 control subjects used a vascular entoptoscope to measure their FAZ diameters.
The disease-related increase in FAZ diameter is large (approximately 400 microm) compared to the repeatability of the entoptic measurement within a subject (SD approximately 35 microm).
Entoptic measurements have the repeatability necessary to reliably monitor increases in FAZ diameter of the magnitude of those induced by diabetes.</description><identifier>ISSN: 1040-5488</identifier><identifier>EISSN: 1538-9235</identifier><identifier>DOI: 10.1097/00006324-199912000-00017</identifier><identifier>PMID: 10612403</identifier><identifier>CODEN: OVSCET</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Biological and medical sciences ; Diabetic Retinopathy - diagnosis ; Diseases ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Female ; Fovea Centralis - pathology ; Humans ; Male ; Medical sciences ; Middle Aged ; Noninvasive medical procedures ; Ophthalmology ; Optics and Photonics ; Optometry - methods ; Reproducibility of Results ; Retinopathies ; Severity of Illness Index ; Tumors. Hypoglycemia ; Vision ; Vision, Entoptic ; Visualization</subject><ispartof>Optometry and vision science, 1999-12, Vol.76 (12), p.826-831</ispartof><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-54464de765bc18327b786012cc8007c6efc428481c56fe77a97de83000c624f53</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1224869$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10612403$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HILMANTEL, G</creatorcontrib><creatorcontrib>APPLEGATE, R. A</creatorcontrib><creatorcontrib>VAN HEUVEN, W. A. J</creatorcontrib><creatorcontrib>STOWERS, S. P</creatorcontrib><creatorcontrib>BRADLEY, A</creatorcontrib><creatorcontrib>LEE, R. L</creatorcontrib><title>Entoptic foveal avascular zone measurement and diabetic retinopathy</title><title>Optometry and vision science</title><addtitle>Optom Vis Sci</addtitle><description>Entoptic visualization of the foveal avascular zone (FAZ) provides a noninvasive method for measurement of the FAZ. To determine if repeatability of measurement with this technique is good enough to monitor changes in diabetic retinopathy, we quantify (1) the repeatability of entoptic FAZ measurement in healthy subjects and (2) the relationship between measured FAZ diameter and the severity of retinopathy.
(1) To determine FAZ measurement repeatability, 10 healthy adults entoptically measured their FAZ diameters in 11 separate testing sessions. (2) In a separate experiment, 53 patients with varying levels of diabetic retinopathy and 21 control subjects used a vascular entoptoscope to measure their FAZ diameters.
The disease-related increase in FAZ diameter is large (approximately 400 microm) compared to the repeatability of the entoptic measurement within a subject (SD approximately 35 microm).
Entoptic measurements have the repeatability necessary to reliably monitor increases in FAZ diameter of the magnitude of those induced by diabetes.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Diabetic Retinopathy - diagnosis</subject><subject>Diseases</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Female</subject><subject>Fovea Centralis - pathology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Noninvasive medical procedures</subject><subject>Ophthalmology</subject><subject>Optics and Photonics</subject><subject>Optometry - methods</subject><subject>Reproducibility of Results</subject><subject>Retinopathies</subject><subject>Severity of Illness Index</subject><subject>Tumors. 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Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Female</topic><topic>Fovea Centralis - pathology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Noninvasive medical procedures</topic><topic>Ophthalmology</topic><topic>Optics and Photonics</topic><topic>Optometry - methods</topic><topic>Reproducibility of Results</topic><topic>Retinopathies</topic><topic>Severity of Illness Index</topic><topic>Tumors. Hypoglycemia</topic><topic>Vision</topic><topic>Vision, Entoptic</topic><topic>Visualization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HILMANTEL, G</creatorcontrib><creatorcontrib>APPLEGATE, R. A</creatorcontrib><creatorcontrib>VAN HEUVEN, W. A. J</creatorcontrib><creatorcontrib>STOWERS, S. P</creatorcontrib><creatorcontrib>BRADLEY, A</creatorcontrib><creatorcontrib>LEE, R. 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L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Entoptic foveal avascular zone measurement and diabetic retinopathy</atitle><jtitle>Optometry and vision science</jtitle><addtitle>Optom Vis Sci</addtitle><date>1999-12-01</date><risdate>1999</risdate><volume>76</volume><issue>12</issue><spage>826</spage><epage>831</epage><pages>826-831</pages><issn>1040-5488</issn><eissn>1538-9235</eissn><coden>OVSCET</coden><abstract>Entoptic visualization of the foveal avascular zone (FAZ) provides a noninvasive method for measurement of the FAZ. To determine if repeatability of measurement with this technique is good enough to monitor changes in diabetic retinopathy, we quantify (1) the repeatability of entoptic FAZ measurement in healthy subjects and (2) the relationship between measured FAZ diameter and the severity of retinopathy.
(1) To determine FAZ measurement repeatability, 10 healthy adults entoptically measured their FAZ diameters in 11 separate testing sessions. (2) In a separate experiment, 53 patients with varying levels of diabetic retinopathy and 21 control subjects used a vascular entoptoscope to measure their FAZ diameters.
The disease-related increase in FAZ diameter is large (approximately 400 microm) compared to the repeatability of the entoptic measurement within a subject (SD approximately 35 microm).
Entoptic measurements have the repeatability necessary to reliably monitor increases in FAZ diameter of the magnitude of those induced by diabetes.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>10612403</pmid><doi>10.1097/00006324-199912000-00017</doi><tpages>6</tpages></addata></record> |
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| issn | 1040-5488 1538-9235 |
| language | eng |
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| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Ovid Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Adult Biological and medical sciences Diabetic Retinopathy - diagnosis Diseases Endocrine pancreas. Apud cells (diseases) Endocrinopathies Female Fovea Centralis - pathology Humans Male Medical sciences Middle Aged Noninvasive medical procedures Ophthalmology Optics and Photonics Optometry - methods Reproducibility of Results Retinopathies Severity of Illness Index Tumors. Hypoglycemia Vision Vision, Entoptic Visualization |
| title | Entoptic foveal avascular zone measurement and diabetic retinopathy |
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