Hemodilution does not alter the coronary vasodilating effects of endogenous or exogenous nitric oxide

Introduction: It is well known that hemoglobin is a scavenger of nitric oxide (NO). The present study used a canine model to test the hypothesis that acute normovolemic hemodilution (ANH) affects NO-mediated coronary vasodilation. Methods: Studies were performed in 18 open-chest, anesthetized dogs....

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Veröffentlicht in:	Canadian journal of anesthesia 2008-08, Vol.55 (8), p.507-514
Hauptverfasser:	Crystal, George J., El-Orbany, Mohammad, Zhou, Xiping, Salem, M. Ramez, Kim, Song-Jung
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Adenosine - pharmacology Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthesiology Animals Biological and medical sciences Blood Gas Analysis Blood Pressure - drug effects Cardiology Circulatory system Coronary Vessels - diagnostic imaging Coronary Vessels - drug effects Critical Care Medicine Dogs Enzyme Inhibitors - pharmacology Female Free Radical Scavengers - pharmacology Heart Rate - drug effects Hemodilution - adverse effects Hemodilution - methods Intensive Male Medical sciences Medicine Medicine & Public Health Models, Animal NG-Nitroarginine Methyl Ester - pharmacology Nitric oxide Nitric Oxide - pharmacology Nitric Oxide - physiology Nitric Oxide Synthase - antagonists & inhibitors Nitroprusside - pharmacology Pain Medicine Pediatrics Pneumology/Respiratory System Radionuclide Imaging Reports Of Original Investigations Treatment Outcome Vasodilator Agents - pharmacology
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