Central Pontine Lesions Observed with MRI in Four Diabetic Patients
We report four diabetic patients with a central pontine lesion on magnetic resonance imaging (MRI). All patients also had hypertension, diabetic neuropathy and nephropathy, and three had chronic hepatitis C. Their neurological symptoms were disproportionately mild compared with the MRI features, whi...
Gespeichert in:
| Veröffentlicht in: | Internal Medicine 2008, Vol.47(15), pp.1425-1430 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1430 |
|---|---|
| container_issue | 15 |
| container_start_page | 1425 |
| container_title | Internal Medicine |
| container_volume | 47 |
| creator | Ichikawa, Hiroo Murakami, Hidetomo Katoh, Hirotaka Hieda, Soutaro Kawamura, Mitsuru |
| description | We report four diabetic patients with a central pontine lesion on magnetic resonance imaging (MRI). All patients also had hypertension, diabetic neuropathy and nephropathy, and three had chronic hepatitis C. Their neurological symptoms were disproportionately mild compared with the MRI features, which were of high intensity on T2-weighted images, but were less prominent on T1- and diffusion-weighted images. A subclinical pontine lesion was found in two patients who had undergone MRI previously. We consider that diabetes mellitus is an important factor for developing a pontine lesion with or without symptoms, probably in association with hepato-renal problems and hypertension. |
| doi_str_mv | 10.2169/internalmedicine.47.0868 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69371037</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69371037</sourcerecordid><originalsourceid>FETCH-LOGICAL-c525t-6a81adf6fa73b58aa3d0ad894ebe7715af131369af53e458e1a24283003352cf3</originalsourceid><addsrcrecordid>eNptkMtKxDAUhoMoOl5eQbJy1zGXpkmXMl5hZER0HU7bU410Uk0yim9vZAYFcXOyON__n_ARQjmbCl7Vp84nDB6GJXaudR6npZ4yU5ktMuGyrAstpNomE1ZzU4g89sh-jC-MSaNrsUv2uKk044pNyGyGPgUY6N3oU26ic4xu9JEumojhHTv64dIzvb2_oc7Ty3EV6LmDBpNr6R0kl9PxkOz0MEQ82rwH5PHy4mF2XcwXVzezs3nRKqFSUYHh0PVVD1o2ygDIjkFn6hIb1Jor6LnksqqhVxJLZZCDKIWR-dtSibaXB-Rk3fsaxrcVxmSXLrY4DOBxXEVb1VJzJnUGzRpswxhjwN6-BreE8Gk5s98C7V-BttT2W2COHm9urJq8_A1ujGVgsQZeYoIn_AEgZCUD_tvM1WbyUqgfsn2GYNHLL2uVjjw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69371037</pqid></control><display><type>article</type><title>Central Pontine Lesions Observed with MRI in Four Diabetic Patients</title><source>J-STAGE Free</source><source>MEDLINE</source><creator>Ichikawa, Hiroo ; Murakami, Hidetomo ; Katoh, Hirotaka ; Hieda, Soutaro ; Kawamura, Mitsuru</creator><creatorcontrib>Ichikawa, Hiroo ; Murakami, Hidetomo ; Katoh, Hirotaka ; Hieda, Soutaro ; Kawamura, Mitsuru</creatorcontrib><description>We report four diabetic patients with a central pontine lesion on magnetic resonance imaging (MRI). All patients also had hypertension, diabetic neuropathy and nephropathy, and three had chronic hepatitis C. Their neurological symptoms were disproportionately mild compared with the MRI features, which were of high intensity on T2-weighted images, but were less prominent on T1- and diffusion-weighted images. A subclinical pontine lesion was found in two patients who had undergone MRI previously. We consider that diabetes mellitus is an important factor for developing a pontine lesion with or without symptoms, probably in association with hepato-renal problems and hypertension.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.47.0868</identifier><identifier>PMID: 18670150</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>central pontine myelinolysis ; chronic hepatitis C ; diabetes mellitus ; Diabetes Mellitus - physiopathology ; Female ; Hepatitis C, Chronic - physiopathology ; Humans ; hypertension ; Hypertension - physiopathology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myelinolysis, Central Pontine - diagnosis ; Myelinolysis, Central Pontine - epidemiology ; Myelinolysis, Central Pontine - physiopathology ; pontine lesion ; Risk Factors</subject><ispartof>Internal Medicine, 2008, Vol.47(15), pp.1425-1430</ispartof><rights>2008 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c525t-6a81adf6fa73b58aa3d0ad894ebe7715af131369af53e458e1a24283003352cf3</citedby><cites>FETCH-LOGICAL-c525t-6a81adf6fa73b58aa3d0ad894ebe7715af131369af53e458e1a24283003352cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18670150$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ichikawa, Hiroo</creatorcontrib><creatorcontrib>Murakami, Hidetomo</creatorcontrib><creatorcontrib>Katoh, Hirotaka</creatorcontrib><creatorcontrib>Hieda, Soutaro</creatorcontrib><creatorcontrib>Kawamura, Mitsuru</creatorcontrib><title>Central Pontine Lesions Observed with MRI in Four Diabetic Patients</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>We report four diabetic patients with a central pontine lesion on magnetic resonance imaging (MRI). All patients also had hypertension, diabetic neuropathy and nephropathy, and three had chronic hepatitis C. Their neurological symptoms were disproportionately mild compared with the MRI features, which were of high intensity on T2-weighted images, but were less prominent on T1- and diffusion-weighted images. A subclinical pontine lesion was found in two patients who had undergone MRI previously. We consider that diabetes mellitus is an important factor for developing a pontine lesion with or without symptoms, probably in association with hepato-renal problems and hypertension.</description><subject>central pontine myelinolysis</subject><subject>chronic hepatitis C</subject><subject>diabetes mellitus</subject><subject>Diabetes Mellitus - physiopathology</subject><subject>Female</subject><subject>Hepatitis C, Chronic - physiopathology</subject><subject>Humans</subject><subject>hypertension</subject><subject>Hypertension - physiopathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myelinolysis, Central Pontine - diagnosis</subject><subject>Myelinolysis, Central Pontine - epidemiology</subject><subject>Myelinolysis, Central Pontine - physiopathology</subject><subject>pontine lesion</subject><subject>Risk Factors</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkMtKxDAUhoMoOl5eQbJy1zGXpkmXMl5hZER0HU7bU410Uk0yim9vZAYFcXOyON__n_ARQjmbCl7Vp84nDB6GJXaudR6npZ4yU5ktMuGyrAstpNomE1ZzU4g89sh-jC-MSaNrsUv2uKk044pNyGyGPgUY6N3oU26ic4xu9JEumojhHTv64dIzvb2_oc7Ty3EV6LmDBpNr6R0kl9PxkOz0MEQ82rwH5PHy4mF2XcwXVzezs3nRKqFSUYHh0PVVD1o2ygDIjkFn6hIb1Jor6LnksqqhVxJLZZCDKIWR-dtSibaXB-Rk3fsaxrcVxmSXLrY4DOBxXEVb1VJzJnUGzRpswxhjwN6-BreE8Gk5s98C7V-BttT2W2COHm9urJq8_A1ujGVgsQZeYoIn_AEgZCUD_tvM1WbyUqgfsn2GYNHLL2uVjjw</recordid><startdate>20080101</startdate><enddate>20080101</enddate><creator>Ichikawa, Hiroo</creator><creator>Murakami, Hidetomo</creator><creator>Katoh, Hirotaka</creator><creator>Hieda, Soutaro</creator><creator>Kawamura, Mitsuru</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080101</creationdate><title>Central Pontine Lesions Observed with MRI in Four Diabetic Patients</title><author>Ichikawa, Hiroo ; Murakami, Hidetomo ; Katoh, Hirotaka ; Hieda, Soutaro ; Kawamura, Mitsuru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c525t-6a81adf6fa73b58aa3d0ad894ebe7715af131369af53e458e1a24283003352cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>central pontine myelinolysis</topic><topic>chronic hepatitis C</topic><topic>diabetes mellitus</topic><topic>Diabetes Mellitus - physiopathology</topic><topic>Female</topic><topic>Hepatitis C, Chronic - physiopathology</topic><topic>Humans</topic><topic>hypertension</topic><topic>Hypertension - physiopathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myelinolysis, Central Pontine - diagnosis</topic><topic>Myelinolysis, Central Pontine - epidemiology</topic><topic>Myelinolysis, Central Pontine - physiopathology</topic><topic>pontine lesion</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ichikawa, Hiroo</creatorcontrib><creatorcontrib>Murakami, Hidetomo</creatorcontrib><creatorcontrib>Katoh, Hirotaka</creatorcontrib><creatorcontrib>Hieda, Soutaro</creatorcontrib><creatorcontrib>Kawamura, Mitsuru</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ichikawa, Hiroo</au><au>Murakami, Hidetomo</au><au>Katoh, Hirotaka</au><au>Hieda, Soutaro</au><au>Kawamura, Mitsuru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central Pontine Lesions Observed with MRI in Four Diabetic Patients</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2008-01-01</date><risdate>2008</risdate><volume>47</volume><issue>15</issue><spage>1425</spage><epage>1430</epage><pages>1425-1430</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>We report four diabetic patients with a central pontine lesion on magnetic resonance imaging (MRI). All patients also had hypertension, diabetic neuropathy and nephropathy, and three had chronic hepatitis C. Their neurological symptoms were disproportionately mild compared with the MRI features, which were of high intensity on T2-weighted images, but were less prominent on T1- and diffusion-weighted images. A subclinical pontine lesion was found in two patients who had undergone MRI previously. We consider that diabetes mellitus is an important factor for developing a pontine lesion with or without symptoms, probably in association with hepato-renal problems and hypertension.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>18670150</pmid><doi>10.2169/internalmedicine.47.0868</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0918-2918 |
| ispartof | Internal Medicine, 2008, Vol.47(15), pp.1425-1430 |
| issn | 0918-2918 1349-7235 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69371037 |
| source | J-STAGE Free; MEDLINE |
| subjects | central pontine myelinolysis chronic hepatitis C diabetes mellitus Diabetes Mellitus - physiopathology Female Hepatitis C, Chronic - physiopathology Humans hypertension Hypertension - physiopathology Magnetic Resonance Imaging Male Middle Aged Myelinolysis, Central Pontine - diagnosis Myelinolysis, Central Pontine - epidemiology Myelinolysis, Central Pontine - physiopathology pontine lesion Risk Factors |
| title | Central Pontine Lesions Observed with MRI in Four Diabetic Patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-20T10%3A00%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Central%20Pontine%20Lesions%20Observed%20with%20MRI%20in%20Four%20Diabetic%20Patients&rft.jtitle=Internal%20Medicine&rft.au=Ichikawa,%20Hiroo&rft.date=2008-01-01&rft.volume=47&rft.issue=15&rft.spage=1425&rft.epage=1430&rft.pages=1425-1430&rft.issn=0918-2918&rft.eissn=1349-7235&rft_id=info:doi/10.2169/internalmedicine.47.0868&rft_dat=%3Cproquest_cross%3E69371037%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69371037&rft_id=info:pmid/18670150&rfr_iscdi=true |