Phenotypic characterisation of a Neospora caninum temperature-sensitive strain in normal and immunodeficient mice

The in vivo persistence, immunogenicity and pathogenicity of a recently described temperature-sensitive (ts) strain from Neospora caninum, NCts-8, was investigated in normal and immunodeficient mice. Groups of BALB/c and SCID/Bg mice were infected s.c. with 5×10 6 wild-type NC-1, control NCts-8 (pas...

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Veröffentlicht in:	International journal for parasitology 1999-10, Vol.29 (10), p.1627-1634
Hauptverfasser:	Dreier, K.J, Stewarter, L.Warren, Kerlin, R.L, Ritter, D.M, Brake, D.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - blood antibody formation Attenuation brain Brain - pathology Coccidiosis - parasitology DNA, Protozoan - analysis experimental infections histopathology Immunogenicity immunoglobulin G Mice Mice, Inbred BALB C Mice, SCID mortality mutants Neospora - genetics Neospora - immunology Neospora - pathogenicity Neospora - physiology Neospora caninum Pathogenicity Persistence Phenotype Polymerase Chain Reaction protozoal infections scid mice Temperature Virulence
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