Ephrin-A5 acts as a repulsive cue for migrating cortical interneurons

Cortical interneurons are born in the germinative zones of the ganglionic eminences in the subpallium, and migrate tangentially in spatially and temporally well‐defined corridors into the neocortex. Because ephrin‐A5 is expressed in the ventricular zone (VZ) of the ganglionic eminences at these deve...

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Veröffentlicht in:	The European journal of neuroscience 2008-07, Vol.28 (1), p.62-73
Hauptverfasser:	Zimmer, Geraldine, Garcez, Patricia, Rudolph, Judith, Niehage, Ronny, Weth, Franco, Lent, Roberto, Bolz, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - anatomy & histology Brain - metabolism Cell Movement - physiology Coculture Techniques Cues ephrin Ephrin-A5 - genetics Ephrin-A5 - metabolism Female Fibroblasts - cytology Fibroblasts - physiology Green Fluorescent Proteins - genetics Green Fluorescent Proteins - metabolism Interneurons - cytology Interneurons - physiology medial ganglionic eminence Mice Mice, Inbred C57BL Mice, Transgenic neuronal migration NIH 3T3 Cells organotypic slice culture Receptor, EphA4 - metabolism Src family tyrosine kinase
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