Effects of Phosphate Injection on Metabolic and Hormonal Responses to Exercise in Fructose-Injected Rats
GHANBARI–NIAKI, A., F. DÉSY AND J.-M. LAVOIE. Effects of phosphate injection on metabolic and hormonal responses to exercise in fructose-injected rats. PHYSIOL BEHAV 67(5) 747–752, 1999.—The purpose of the present study was to evaluate the effects of an intraperitoneal injection of sodium phosphate...
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| creator | Ghanbari–Niaki, Abbass Désy, François Lavoie, Jean-Marc |
| description | GHANBARI–NIAKI, A., F. DÉSY AND J.-M. LAVOIE.
Effects of phosphate injection on metabolic and hormonal responses to exercise in fructose-injected rats. PHYSIOL BEHAV
67(5) 747–752, 1999.—The purpose of the present study was to evaluate the effects of an intraperitoneal injection of sodium phosphate on the metabolic and hormonal responses to exercise. Fructose-injected rats were either injected with sodium phosphate (Na
2HPO
4) or NaCl, either in a fed or in a food-restricted state (24 h), and evaluated at rest or after a 30-min exercise period (26 m/min; 0% grade). Liver ATP, phosphate (Pi), and glycogen concentrations were, on the whole, significantly (
p < 0.05) higher in Na
2HPO
4 than in NaCl groups. Exercise resulted in a significant (
p < 0.01) decrease in liver ATP and glycogen levels in fed and food-restricted rats whether injected with NaCl or Na
2HPO
4. Exercise, after NaCl and Na
2HPO
4 injection, resulted in a significant (
p < 0.01) increase in liver phosphate and Pi/ATP ratio, and in a decrease in glucose and an increase in glucagon levels in food-restricted rats only. The normal exercise-induced increase in plasma FFA, glycerol, and norepinephrine levels (
p < 0.05), observed in both fed and food-restricted NaCl-injected rats, was abolished by the injection of phosphate. The data are in line with the new concept that in addition to blood glucose levels, the increase in liver Pi/ATP ratio could also contribute to the increase in glucagon response during exercise. |
| doi_str_mv | 10.1016/S0031-9384(99)00130-4 |
| format | Article |
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Effects of phosphate injection on metabolic and hormonal responses to exercise in fructose-injected rats. PHYSIOL BEHAV
67(5) 747–752, 1999.—The purpose of the present study was to evaluate the effects of an intraperitoneal injection of sodium phosphate on the metabolic and hormonal responses to exercise. Fructose-injected rats were either injected with sodium phosphate (Na
2HPO
4) or NaCl, either in a fed or in a food-restricted state (24 h), and evaluated at rest or after a 30-min exercise period (26 m/min; 0% grade). Liver ATP, phosphate (Pi), and glycogen concentrations were, on the whole, significantly (
p < 0.05) higher in Na
2HPO
4 than in NaCl groups. Exercise resulted in a significant (
p < 0.01) decrease in liver ATP and glycogen levels in fed and food-restricted rats whether injected with NaCl or Na
2HPO
4. Exercise, after NaCl and Na
2HPO
4 injection, resulted in a significant (
p < 0.01) increase in liver phosphate and Pi/ATP ratio, and in a decrease in glucose and an increase in glucagon levels in food-restricted rats only. The normal exercise-induced increase in plasma FFA, glycerol, and norepinephrine levels (
p < 0.05), observed in both fed and food-restricted NaCl-injected rats, was abolished by the injection of phosphate. The data are in line with the new concept that in addition to blood glucose levels, the increase in liver Pi/ATP ratio could also contribute to the increase in glucagon response during exercise.</description><identifier>ISSN: 0031-9384</identifier><identifier>EISSN: 1873-507X</identifier><identifier>DOI: 10.1016/S0031-9384(99)00130-4</identifier><identifier>PMID: 10604847</identifier><language>eng</language><publisher>Cambridge: Elsevier Inc</publisher><subject>3-Hydroxybutyric Acid - metabolism ; Adenosine Triphosphate - metabolism ; Animals ; Behavioral psychophysiology ; Biological and medical sciences ; Blood Glucose - metabolism ; Fatty Acids, Nonesterified - metabolism ; Free fatty acids ; Fructose - pharmacology ; Fructose injection ; Fundamental and applied biological sciences. Psychology ; Glucagon ; Hormones - blood ; Liver - cytology ; Liver - drug effects ; Liver - metabolism ; Liver Glycogen - metabolism ; Metabolism - physiology ; Miscellaneous ; Phosphate injection ; Phosphates - administration & dosage ; Phosphates - metabolism ; Phosphates - pharmacology ; Physical Exertion - physiology ; Psychology. Psychoanalysis. Psychiatry ; Psychology. Psychophysiology ; Rats ; Rats, Sprague-Dawley</subject><ispartof>Physiology & behavior, 1999-11, Vol.67 (5), p.747-752</ispartof><rights>1999 Elsevier Science Inc.</rights><rights>2000 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c390t-5b058a1e598bfd691293cfd5d624da35c6eeb13bb41ead5ea401a84fdd71ed393</citedby><cites>FETCH-LOGICAL-c390t-5b058a1e598bfd691293cfd5d624da35c6eeb13bb41ead5ea401a84fdd71ed393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0031-9384(99)00130-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1202728$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10604847$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghanbari–Niaki, Abbass</creatorcontrib><creatorcontrib>Désy, François</creatorcontrib><creatorcontrib>Lavoie, Jean-Marc</creatorcontrib><title>Effects of Phosphate Injection on Metabolic and Hormonal Responses to Exercise in Fructose-Injected Rats</title><title>Physiology & behavior</title><addtitle>Physiol Behav</addtitle><description>GHANBARI–NIAKI, A., F. DÉSY AND J.-M. LAVOIE.
Effects of phosphate injection on metabolic and hormonal responses to exercise in fructose-injected rats. PHYSIOL BEHAV
67(5) 747–752, 1999.—The purpose of the present study was to evaluate the effects of an intraperitoneal injection of sodium phosphate on the metabolic and hormonal responses to exercise. Fructose-injected rats were either injected with sodium phosphate (Na
2HPO
4) or NaCl, either in a fed or in a food-restricted state (24 h), and evaluated at rest or after a 30-min exercise period (26 m/min; 0% grade). Liver ATP, phosphate (Pi), and glycogen concentrations were, on the whole, significantly (
p < 0.05) higher in Na
2HPO
4 than in NaCl groups. Exercise resulted in a significant (
p < 0.01) decrease in liver ATP and glycogen levels in fed and food-restricted rats whether injected with NaCl or Na
2HPO
4. Exercise, after NaCl and Na
2HPO
4 injection, resulted in a significant (
p < 0.01) increase in liver phosphate and Pi/ATP ratio, and in a decrease in glucose and an increase in glucagon levels in food-restricted rats only. The normal exercise-induced increase in plasma FFA, glycerol, and norepinephrine levels (
p < 0.05), observed in both fed and food-restricted NaCl-injected rats, was abolished by the injection of phosphate. The data are in line with the new concept that in addition to blood glucose levels, the increase in liver Pi/ATP ratio could also contribute to the increase in glucagon response during exercise.</description><subject>3-Hydroxybutyric Acid - metabolism</subject><subject>Adenosine Triphosphate - metabolism</subject><subject>Animals</subject><subject>Behavioral psychophysiology</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Fatty Acids, Nonesterified - metabolism</subject><subject>Free fatty acids</subject><subject>Fructose - pharmacology</subject><subject>Fructose injection</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glucagon</subject><subject>Hormones - blood</subject><subject>Liver - cytology</subject><subject>Liver - drug effects</subject><subject>Liver - metabolism</subject><subject>Liver Glycogen - metabolism</subject><subject>Metabolism - physiology</subject><subject>Miscellaneous</subject><subject>Phosphate injection</subject><subject>Phosphates - administration & dosage</subject><subject>Phosphates - metabolism</subject><subject>Phosphates - pharmacology</subject><subject>Physical Exertion - physiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychology. Psychophysiology</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><issn>0031-9384</issn><issn>1873-507X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkFtrFDEUgEOxtGv1J1TyIGIfRpNJ5pInkbK9QEWpCn0LmeSETZlN1pxZqf--aWdpfevhwIHDdy58hBxz9okz3n7-yZjglRK9_KjUCWNcsErukQXvO1E1rLt5RRZPyCF5jXjLSggpDsghZy2TvewWZLX0HuyENHn6Y5VwszIT0Mt4W5ohRVryG0xmSGOw1ERHL1Jep2hGeg24SREB6ZTo8g6yDQg0RHqWt3ZKCNW8BRy9NhO-IfvejAhvd_WI_D5b_jq9qK6-n1-efr2qrFBsqpqBNb3h0Kh-8K5VvFbCete4tpbOiMa2AAMXwyA5GNeAkYybXnrnOg5OKHFEPsx7Nzn92QJOeh3QwjiaCGmLulWirUXNC9jMoM0JMYPXmxzWJv_TnOkHxfpRsX7wp5XSj4q1LHPvdge2wxrcf1Oz0wK83wEGrRl9NrGoeeZqVnd1X7AvMwbFxt8AWaMNEC24kIs27VJ44ZN7YsyZNw</recordid><startdate>19991101</startdate><enddate>19991101</enddate><creator>Ghanbari–Niaki, Abbass</creator><creator>Désy, François</creator><creator>Lavoie, Jean-Marc</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19991101</creationdate><title>Effects of Phosphate Injection on Metabolic and Hormonal Responses to Exercise in Fructose-Injected Rats</title><author>Ghanbari–Niaki, Abbass ; Désy, François ; Lavoie, Jean-Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-5b058a1e598bfd691293cfd5d624da35c6eeb13bb41ead5ea401a84fdd71ed393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>3-Hydroxybutyric Acid - metabolism</topic><topic>Adenosine Triphosphate - metabolism</topic><topic>Animals</topic><topic>Behavioral psychophysiology</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - metabolism</topic><topic>Fatty Acids, Nonesterified - metabolism</topic><topic>Free fatty acids</topic><topic>Fructose - pharmacology</topic><topic>Fructose injection</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glucagon</topic><topic>Hormones - blood</topic><topic>Liver - cytology</topic><topic>Liver - drug effects</topic><topic>Liver - metabolism</topic><topic>Liver Glycogen - metabolism</topic><topic>Metabolism - physiology</topic><topic>Miscellaneous</topic><topic>Phosphate injection</topic><topic>Phosphates - administration & dosage</topic><topic>Phosphates - metabolism</topic><topic>Phosphates - pharmacology</topic><topic>Physical Exertion - physiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychology. Psychophysiology</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghanbari–Niaki, Abbass</creatorcontrib><creatorcontrib>Désy, François</creatorcontrib><creatorcontrib>Lavoie, Jean-Marc</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Physiology & behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghanbari–Niaki, Abbass</au><au>Désy, François</au><au>Lavoie, Jean-Marc</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of Phosphate Injection on Metabolic and Hormonal Responses to Exercise in Fructose-Injected Rats</atitle><jtitle>Physiology & behavior</jtitle><addtitle>Physiol Behav</addtitle><date>1999-11-01</date><risdate>1999</risdate><volume>67</volume><issue>5</issue><spage>747</spage><epage>752</epage><pages>747-752</pages><issn>0031-9384</issn><eissn>1873-507X</eissn><abstract>GHANBARI–NIAKI, A., F. DÉSY AND J.-M. LAVOIE.
Effects of phosphate injection on metabolic and hormonal responses to exercise in fructose-injected rats. PHYSIOL BEHAV
67(5) 747–752, 1999.—The purpose of the present study was to evaluate the effects of an intraperitoneal injection of sodium phosphate on the metabolic and hormonal responses to exercise. Fructose-injected rats were either injected with sodium phosphate (Na
2HPO
4) or NaCl, either in a fed or in a food-restricted state (24 h), and evaluated at rest or after a 30-min exercise period (26 m/min; 0% grade). Liver ATP, phosphate (Pi), and glycogen concentrations were, on the whole, significantly (
p < 0.05) higher in Na
2HPO
4 than in NaCl groups. Exercise resulted in a significant (
p < 0.01) decrease in liver ATP and glycogen levels in fed and food-restricted rats whether injected with NaCl or Na
2HPO
4. Exercise, after NaCl and Na
2HPO
4 injection, resulted in a significant (
p < 0.01) increase in liver phosphate and Pi/ATP ratio, and in a decrease in glucose and an increase in glucagon levels in food-restricted rats only. The normal exercise-induced increase in plasma FFA, glycerol, and norepinephrine levels (
p < 0.05), observed in both fed and food-restricted NaCl-injected rats, was abolished by the injection of phosphate. The data are in line with the new concept that in addition to blood glucose levels, the increase in liver Pi/ATP ratio could also contribute to the increase in glucagon response during exercise.</abstract><cop>Cambridge</cop><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10604847</pmid><doi>10.1016/S0031-9384(99)00130-4</doi><tpages>6</tpages></addata></record> |
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| ispartof | Physiology & behavior, 1999-11, Vol.67 (5), p.747-752 |
| issn | 0031-9384 1873-507X |
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| subjects | 3-Hydroxybutyric Acid - metabolism Adenosine Triphosphate - metabolism Animals Behavioral psychophysiology Biological and medical sciences Blood Glucose - metabolism Fatty Acids, Nonesterified - metabolism Free fatty acids Fructose - pharmacology Fructose injection Fundamental and applied biological sciences. Psychology Glucagon Hormones - blood Liver - cytology Liver - drug effects Liver - metabolism Liver Glycogen - metabolism Metabolism - physiology Miscellaneous Phosphate injection Phosphates - administration & dosage Phosphates - metabolism Phosphates - pharmacology Physical Exertion - physiology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley |
| title | Effects of Phosphate Injection on Metabolic and Hormonal Responses to Exercise in Fructose-Injected Rats |
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