Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network

The regulation and maintenance of systemic iron homeostasis is critical to human health. Iron overload and deficiency diseases belong to the most common nutrition-related pathologies across the globe. It is now well appreciated that the hormonal hepcidin/ferroportin system plays an important regulat...

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Veröffentlicht in:	Annual review of nutrition 2008-01, Vol.28 (1), p.197-213
Hauptverfasser:	Muckenthaler, Martina U, Galy, Bruno, Hentze, Matthias W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals biochemical pathways Biological and medical sciences deficiency diseases dietary minerals Feeding. Feeding behavior ferroportin Fundamental and applied biological sciences. Psychology hepcidin Homeostasis Humans iron Iron - blood Iron - deficiency Iron-Regulatory Proteins - physiology literature reviews mineral metabolism nutrient deficiencies nutrient excess peptide hormones Response Elements - physiology transmembrane proteins transport proteins Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
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