Malignant rhabdoid tumor beside benign skin mesenchymal neoplasm with myofibromatous features

Only a few reports of primary cutaneous rhabdoid tumors have been published. We describe the case of a 3‐month‐old female patient who developed a rhabdoid type cutaneous sareomatoid neoplasm in her upper back, close to a benign myofibromatous proliferation of infancy. The lesion was studied both by...

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Veröffentlicht in:Journal of cutaneous pathology 1999-11, Vol.26 (10), p.509-515
Hauptverfasser: García-Bustínduy, Marta, Álvarez-Arguelles, Hugo, Guimerá, Francisco, García-Castro, Candelaria, Sánchez-González, Rosalba, Hernández, Norberto, Diaz-Flores, Lucio, García-Montelongo, Rafael
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container_end_page 515
container_issue 10
container_start_page 509
container_title Journal of cutaneous pathology
container_volume 26
creator García-Bustínduy, Marta
Álvarez-Arguelles, Hugo
Guimerá, Francisco
García-Castro, Candelaria
Sánchez-González, Rosalba
Hernández, Norberto
Diaz-Flores, Lucio
García-Montelongo, Rafael
description Only a few reports of primary cutaneous rhabdoid tumors have been published. We describe the case of a 3‐month‐old female patient who developed a rhabdoid type cutaneous sareomatoid neoplasm in her upper back, close to a benign myofibromatous proliferation of infancy. The lesion was studied both by light microscopy and immunohisto‐chemically. Flow cytometry was performed showing a DNA diploid profile of the malignant tumor. The pathological findings suggest a mesenchymal origin (hemangiopericytic or myofibroblastic type) for both tumors. The patient was surgically treated, but she died nine months later.
doi_str_mv 10.1111/j.1600-0560.1999.tb01798.x
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We describe the case of a 3‐month‐old female patient who developed a rhabdoid type cutaneous sareomatoid neoplasm in her upper back, close to a benign myofibromatous proliferation of infancy. The lesion was studied both by light microscopy and immunohisto‐chemically. Flow cytometry was performed showing a DNA diploid profile of the malignant tumor. The pathological findings suggest a mesenchymal origin (hemangiopericytic or myofibroblastic type) for both tumors. 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We describe the case of a 3‐month‐old female patient who developed a rhabdoid type cutaneous sareomatoid neoplasm in her upper back, close to a benign myofibromatous proliferation of infancy. The lesion was studied both by light microscopy and immunohisto‐chemically. Flow cytometry was performed showing a DNA diploid profile of the malignant tumor. The pathological findings suggest a mesenchymal origin (hemangiopericytic or myofibroblastic type) for both tumors. The patient was surgically treated, but she died nine months later.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>10599942</pmid><doi>10.1111/j.1600-0560.1999.tb01798.x</doi><tpages>7</tpages></addata></record>
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subjects Biological and medical sciences
Biomarkers, Tumor - analysis
Cell Separation
Dermatology
DNA, Neoplasm - analysis
Fatal Outcome
Female
Flow Cytometry
Humans
Immunoenzyme Techniques
Infant
Medical sciences
Mesenchymoma - chemistry
Mesenchymoma - genetics
Mesenchymoma - pathology
Mesenchymoma - surgery
Neoplasms, Multiple Primary - chemistry
Neoplasms, Multiple Primary - genetics
Neoplasms, Multiple Primary - pathology
Neoplasms, Multiple Primary - surgery
Ploidies
Rhabdoid Tumor - chemistry
Rhabdoid Tumor - genetics
Rhabdoid Tumor - pathology
Rhabdoid Tumor - surgery
Skin Neoplasms - chemistry
Skin Neoplasms - genetics
Skin Neoplasms - pathology
Skin Neoplasms - surgery
Tumors of the skin and soft tissue. Premalignant lesions
title Malignant rhabdoid tumor beside benign skin mesenchymal neoplasm with myofibromatous features
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