CD83 regulates splenic B cell maturation and peripheral B cell homeostasis

The central function of murine CD83 that is expressed on thymic epithelial cells is to induce the progression of double-positive thymocytes to single CD4-positive T cells. Several lines of evidence suggest an additional role for CD83 in the regulation of peripheral T and B cell responses. Here we sh...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International immunology 2008-08, Vol.20 (8), p.949-960
Hauptverfasser:	Lüthje, Katja, Kretschmer, Birte, Fleischer, Bernhard, Breloer, Minka
Format:	Artikel
Sprache:	eng
Schlagworte:	Adoptive Transfer Animals Antigens, CD - biosynthesis Antigens, CD - genetics Antigens, CD - immunology B cell homeostasis B cell maturation B-Lymphocytes - drug effects B-Lymphocytes - immunology B-Lymphocytes - metabolism Bone Marrow Transplantation CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism CD83 CD83 Antigen Cell Differentiation - drug effects Cell Differentiation - immunology Cell Survival - drug effects Cell Survival - immunology Feedback, Physiological - immunology Immunoglobulins - biosynthesis Immunoglobulins - genetics Immunoglobulins - immunology Lipopolysaccharides - pharmacology Lymphocyte Activation - drug effects Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Spleen - cytology Spleen - drug effects Spleen - immunology Spleen - metabolism transgenic mice
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!