Metabolic Control with Insulin Pump Therapy: Preliminary Experience
Background The benefits of insulin pump therapy on the metabolic control of both type 1 and type 2 diabetes have been reported. Such reports have prompted our interest to investigate the long-term metabolic effects of insulin pump therapy at our institution. Methods We retrospectively analyzed the m...
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| Veröffentlicht in: | Journal of the Chinese Medical Association 2008-07, Vol.71 (7), p.353-356 |
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| container_title | Journal of the Chinese Medical Association |
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| creator | Hsu, Shang-Ren Lin, Shi-Dou Tu, Shih-Te Liao, Pei-Yung Su, Shih-Li Lin, Su-Lan Tseng, Ya-Yu Huang, Pei-Wen |
| description | Background The benefits of insulin pump therapy on the metabolic control of both type 1 and type 2 diabetes have been reported. Such reports have prompted our interest to investigate the long-term metabolic effects of insulin pump therapy at our institution. Methods We retrospectively analyzed the management of type 1 and type 2 diabetic patients who began extended insulin pump therapy at Changhua Christian Hospital between November 2004 and October 2007. One-way ANOVA and post hoc analysis were used to compare baseline glycosylated hemoglobin (HbA1C) values with subsequent values. Results We studied 12 patients who were on continuous subcutaneous insulin infusion (CSII) therapy at the time of data collection. Mean duration of CSII therapy was 2.3 years. A reduction in HbA1C was found after administering CSII, which was sustained after 1, 2 and 3 years of therapy (7.0%, 6.7% and 6.6%, respectively), with statistical significance ( p |
| doi_str_mv | 10.1016/S1726-4901(08)70138-2 |
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Such reports have prompted our interest to investigate the long-term metabolic effects of insulin pump therapy at our institution. Methods We retrospectively analyzed the management of type 1 and type 2 diabetic patients who began extended insulin pump therapy at Changhua Christian Hospital between November 2004 and October 2007. One-way ANOVA and post hoc analysis were used to compare baseline glycosylated hemoglobin (HbA1C) values with subsequent values. Results We studied 12 patients who were on continuous subcutaneous insulin infusion (CSII) therapy at the time of data collection. Mean duration of CSII therapy was 2.3 years. A reduction in HbA1C was found after administering CSII, which was sustained after 1, 2 and 3 years of therapy (7.0%, 6.7% and 6.6%, respectively), with statistical significance ( p <0.05). No incidence of severe hypoglycemia or diabetic ketoacidosis occurred during the treatment period. Conclusion Our preliminary experience demonstrated the effectiveness of insulin pump therapy for both type 1 and type 2 diabetic patients. The reduction in their HbA1C values was both statistically and clinically significant. This treatment should be considered for patients poorly controlled by subcutaneous insulin injection therapy.</description><identifier>ISSN: 1726-4901</identifier><identifier>EISSN: 1728-7731</identifier><identifier>DOI: 10.1016/S1726-4901(08)70138-2</identifier><identifier>PMID: 18653398</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adult ; continuous subcutaneous insulin infusion (CSII) ; Diabetes Mellitus - metabolism ; diabetic ketoacidosis ; Female ; Glycated Hemoglobin A - analysis ; glycosylated hemoglobin A (HbA1C) ; Humans ; Insulin Infusion Systems ; Internal Medicine ; Male ; Retrospective Studies</subject><ispartof>Journal of the Chinese Medical Association, 2008-07, Vol.71 (7), p.353-356</ispartof><rights>Elsevier</rights><rights>2008 Elsevier</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-b9562c087e6b78acf821a2b4074419193c0d6e25c8c0bfdec0b1ab52097be363</citedby><cites>FETCH-LOGICAL-c465t-b9562c087e6b78acf821a2b4074419193c0d6e25c8c0bfdec0b1ab52097be363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1726490108701382$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18653398$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hsu, Shang-Ren</creatorcontrib><creatorcontrib>Lin, Shi-Dou</creatorcontrib><creatorcontrib>Tu, Shih-Te</creatorcontrib><creatorcontrib>Liao, Pei-Yung</creatorcontrib><creatorcontrib>Su, Shih-Li</creatorcontrib><creatorcontrib>Lin, Su-Lan</creatorcontrib><creatorcontrib>Tseng, Ya-Yu</creatorcontrib><creatorcontrib>Huang, Pei-Wen</creatorcontrib><title>Metabolic Control with Insulin Pump Therapy: Preliminary Experience</title><title>Journal of the Chinese Medical Association</title><addtitle>J Chin Med Assoc</addtitle><description>Background The benefits of insulin pump therapy on the metabolic control of both type 1 and type 2 diabetes have been reported. Such reports have prompted our interest to investigate the long-term metabolic effects of insulin pump therapy at our institution. Methods We retrospectively analyzed the management of type 1 and type 2 diabetic patients who began extended insulin pump therapy at Changhua Christian Hospital between November 2004 and October 2007. One-way ANOVA and post hoc analysis were used to compare baseline glycosylated hemoglobin (HbA1C) values with subsequent values. Results We studied 12 patients who were on continuous subcutaneous insulin infusion (CSII) therapy at the time of data collection. Mean duration of CSII therapy was 2.3 years. A reduction in HbA1C was found after administering CSII, which was sustained after 1, 2 and 3 years of therapy (7.0%, 6.7% and 6.6%, respectively), with statistical significance ( p <0.05). No incidence of severe hypoglycemia or diabetic ketoacidosis occurred during the treatment period. Conclusion Our preliminary experience demonstrated the effectiveness of insulin pump therapy for both type 1 and type 2 diabetic patients. The reduction in their HbA1C values was both statistically and clinically significant. This treatment should be considered for patients poorly controlled by subcutaneous insulin injection therapy.</description><subject>Adult</subject><subject>continuous subcutaneous insulin infusion (CSII)</subject><subject>Diabetes Mellitus - metabolism</subject><subject>diabetic ketoacidosis</subject><subject>Female</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>glycosylated hemoglobin A (HbA1C)</subject><subject>Humans</subject><subject>Insulin Infusion Systems</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Retrospective Studies</subject><issn>1726-4901</issn><issn>1728-7731</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtKxDAUhoMoznh5BKUr0UU1lzZNXCgyeBlQFJx9SNMzmLE3k1adtzczHRDcuMkJ4T_fyfkQOiL4nGDCL15JRnmcSExOsTjLMGEipltoHJ5FnGWMbK_vQ2SE9rxfYJxwKdNdNCKCp4xJMUaTJ-h03pTWRJOm7lxTRl-2e4umte9LW0cvfdVGszdwul1eRi8OSlvZWrtldPvdgrNQGzhAO3Ndejjc1H00u7udTR7ix-f76eTmMTYJT7s4lymnBosMeJ4JbeaCEk3zBGdJQiSRzOCCA02NMDifFxBOovOUYpnlwDjbRycDtnXNRw--U5X1BspS19D0XnHJUiYSEoLpEDSu8d7BXLXOVuHPimC1kqfW8tTKjMJCreUpGvqONwP6vILit2tjKwSuhwCELT8tOOXN2kBhHZhOFY39d8TVH4IJlq3R5TsswS-a3tVBoSLKU4UHyIoRrK0IlP0AcxCTLg</recordid><startdate>20080701</startdate><enddate>20080701</enddate><creator>Hsu, Shang-Ren</creator><creator>Lin, Shi-Dou</creator><creator>Tu, Shih-Te</creator><creator>Liao, Pei-Yung</creator><creator>Su, Shih-Li</creator><creator>Lin, Su-Lan</creator><creator>Tseng, Ya-Yu</creator><creator>Huang, Pei-Wen</creator><general>Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080701</creationdate><title>Metabolic Control with Insulin Pump Therapy: Preliminary Experience</title><author>Hsu, Shang-Ren ; Lin, Shi-Dou ; Tu, Shih-Te ; Liao, Pei-Yung ; Su, Shih-Li ; Lin, Su-Lan ; Tseng, Ya-Yu ; Huang, Pei-Wen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-b9562c087e6b78acf821a2b4074419193c0d6e25c8c0bfdec0b1ab52097be363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>continuous subcutaneous insulin infusion (CSII)</topic><topic>Diabetes Mellitus - metabolism</topic><topic>diabetic ketoacidosis</topic><topic>Female</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>glycosylated hemoglobin A (HbA1C)</topic><topic>Humans</topic><topic>Insulin Infusion Systems</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hsu, Shang-Ren</creatorcontrib><creatorcontrib>Lin, Shi-Dou</creatorcontrib><creatorcontrib>Tu, Shih-Te</creatorcontrib><creatorcontrib>Liao, Pei-Yung</creatorcontrib><creatorcontrib>Su, Shih-Li</creatorcontrib><creatorcontrib>Lin, Su-Lan</creatorcontrib><creatorcontrib>Tseng, Ya-Yu</creatorcontrib><creatorcontrib>Huang, Pei-Wen</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Chinese Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hsu, Shang-Ren</au><au>Lin, Shi-Dou</au><au>Tu, Shih-Te</au><au>Liao, Pei-Yung</au><au>Su, Shih-Li</au><au>Lin, Su-Lan</au><au>Tseng, Ya-Yu</au><au>Huang, Pei-Wen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolic Control with Insulin Pump Therapy: Preliminary Experience</atitle><jtitle>Journal of the Chinese Medical Association</jtitle><addtitle>J Chin Med Assoc</addtitle><date>2008-07-01</date><risdate>2008</risdate><volume>71</volume><issue>7</issue><spage>353</spage><epage>356</epage><pages>353-356</pages><issn>1726-4901</issn><eissn>1728-7731</eissn><abstract>Background The benefits of insulin pump therapy on the metabolic control of both type 1 and type 2 diabetes have been reported. Such reports have prompted our interest to investigate the long-term metabolic effects of insulin pump therapy at our institution. Methods We retrospectively analyzed the management of type 1 and type 2 diabetic patients who began extended insulin pump therapy at Changhua Christian Hospital between November 2004 and October 2007. One-way ANOVA and post hoc analysis were used to compare baseline glycosylated hemoglobin (HbA1C) values with subsequent values. Results We studied 12 patients who were on continuous subcutaneous insulin infusion (CSII) therapy at the time of data collection. Mean duration of CSII therapy was 2.3 years. A reduction in HbA1C was found after administering CSII, which was sustained after 1, 2 and 3 years of therapy (7.0%, 6.7% and 6.6%, respectively), with statistical significance ( p <0.05). No incidence of severe hypoglycemia or diabetic ketoacidosis occurred during the treatment period. Conclusion Our preliminary experience demonstrated the effectiveness of insulin pump therapy for both type 1 and type 2 diabetic patients. The reduction in their HbA1C values was both statistically and clinically significant. This treatment should be considered for patients poorly controlled by subcutaneous insulin injection therapy.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>18653398</pmid><doi>10.1016/S1726-4901(08)70138-2</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult continuous subcutaneous insulin infusion (CSII) Diabetes Mellitus - metabolism diabetic ketoacidosis Female Glycated Hemoglobin A - analysis glycosylated hemoglobin A (HbA1C) Humans Insulin Infusion Systems Internal Medicine Male Retrospective Studies |
| title | Metabolic Control with Insulin Pump Therapy: Preliminary Experience |
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