Re-sequencing of DNA from a diverse panel of cattle reveals a high level of polymorphism in both intron and exon

In order to assess the extent of DNA sequence variation in cattle, introns and exons from both the leptin and Amyloid Precursor Protein (APP) genes have been sequenced in a panel of DNAs derived from 22 diverse animals. Direct DNA sequencing of PCR products was used; thus, 44 chromosomes were studie...

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Veröffentlicht in:	Mammalian genome 1999-12, Vol.10 (12), p.1142-1145
Hauptverfasser:	Konfortov, Bernard A, Licence, Victoria E, Miller, J. Ross
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution amyloid Amyloid beta-Protein Precursor - genetics amyloid precursor protein Animals APP gene cattle Cattle - genetics chromosomes Chromosomes - genetics Deoxyribonucleic acid DNA exons Exons - genetics Gene Frequency Genes Genetic Variation - genetics Genetics Genomics Humans introns Introns - genetics leptin Leptin - genetics Mutation - genetics polymerase chain reaction Polymorphism, Genetic - genetics sequence analysis Sequence Analysis, DNA single nucleotide polymorphism
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