Nerve growth factor (NGF) supports tooth morphogenesis in mouse first branchial arch explants

Posterior midbrain and anterior hindbrain neuroectoderm transdifferentiate into cranial neural crest cells (CNCC), emigrate from the neural folds, and become crest‐derived ectomesenchyme within the mandibular and maxillary processes. To investigate the growth factor requirement specific for the init...

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Veröffentlicht in:	Developmental dynamics 1999-11, Vol.216 (3), p.299-310
Hauptverfasser:	Amano, Osamu, Bringas, Pablo, Takahashi, Ichiro, Takahashi, Katsu, Yamane, Akira, Chai, Yang, Nuckolls, Glen H., Shum, Lillian, Slavkin, Harold C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Branchial Region - embryology cartilage Cartilage - cytology Cartilage - embryology Cell Culture Techniques - methods Cell Differentiation Cell Movement Chondrogenesis Culture Techniques DiI‐labeling DNA-Binding Proteins - metabolism Dose-Response Relationship, Drug epidermal growth factor (EGF) Epidermal Growth Factor - metabolism first branchial arch In Situ Hybridization in vitro Mice morphometry myogenesis nerve growth factor (NGF) Nerve Growth Factor - pharmacology Nerve Growth Factor - physiology Neural Crest - cytology Neural Crest - embryology Neural Crest - metabolism odontogenesis Odontogenesis - drug effects Odontogenesis - physiology Pax9 PAX9 Transcription Factor polymerase chain reaction (PCR) Reverse Transcriptase Polymerase Chain Reaction tongue Tongue - cytology Tongue - embryology Tooth - embryology tooth bud Transcription Factors - metabolism whole‐mount in situ hybridization
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