Visceral Leishmaniasis (Kala-azar) in Solid Organ Transplantation: Report of Five Cases and Review

Visceral leishmaniasis is an infectious disease that occurs only rarely in recipients of solid organ grafts but is associated with an elevated mortality rate despite proper treatment. We report five cases diagnosed in our hospital. All the patients were men aged 30 to 60 years who had undergone kidn...

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Veröffentlicht in:Clinical infectious diseases 1999-10, Vol.29 (4), p.918-921
Hauptverfasser: Hernández-Pérez, J., Yebra-Bango, M., Jiménez-Martínez, E., Sanz-Moreno, C., Cuervas-Mons, V., Pulpón, L. Alonso, Ramos-Martínez, A., Fernández-Fernández, J.
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container_end_page 921
container_issue 4
container_start_page 918
container_title Clinical infectious diseases
container_volume 29
creator Hernández-Pérez, J.
Yebra-Bango, M.
Jiménez-Martínez, E.
Sanz-Moreno, C.
Cuervas-Mons, V.
Pulpón, L. Alonso
Ramos-Martínez, A.
Fernández-Fernández, J.
description Visceral leishmaniasis is an infectious disease that occurs only rarely in recipients of solid organ grafts but is associated with an elevated mortality rate despite proper treatment. We report five cases diagnosed in our hospital. All the patients were men aged 30 to 60 years who had undergone kidney transplantation (3 patients), heart transplantation (1), or liver transplantation (1). Three of the patients died, one had multiple recurrences, and one developed post-kala-azar cutaneous leishmaniasis. We review the clinical features, treatments, and outcomes of 26 previously reported cases, pointing out the lower cure rate associated with human immunodeficiency virus infection.
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subjects Adult
AIDS/HIV
Biological and medical sciences
Body weight
Fever
Human protozoal diseases
Humans
Infections
Infectious diseases
Kidneys
Leishmaniasis
Leishmaniasis, Visceral - diagnosis
Leishmaniasis, Visceral - drug therapy
Leishmaniasis, Visceral - etiology
Leshmaniasis
Liver
Male
Medical sciences
Middle Aged
Organ transplantation
Organ Transplantation - adverse effects
Parasitic diseases
Protozoal diseases
Splenomegaly
Transplantation
Visceral leishmaniasis
title Visceral Leishmaniasis (Kala-azar) in Solid Organ Transplantation: Report of Five Cases and Review
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