Down-regulation of Matriptase by Overexpression of Bikunin Attenuates Cell Invasion in Prostate Carcinoma Cells

The precise mechanisms of metastasis in prostatic cancer are still unknown. A subculture cell line (PC-J) was isolated from the metastasis human prostate cell line PC-3. In vitro cell proliferation, wound healing and invasion assays revealed that tumorigenesis and metastasis differed between PC-3 an...

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Veröffentlicht in:	Anticancer research 2008-07, Vol.28 (4A), p.1977-1984
Hauptverfasser:	Tsui, Ke-Hung, Chang, Phei-Lang, Feng, Tsui-Hsia, Chung, Li-Chuan, Hsu, Shu-Yuan, Juang, Horng-Heng
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Globulins - biosynthesis Alpha-Globulins - genetics Animals Cell Line, Tumor Down-Regulation Gene Expression Regulation, Enzymologic Gene Expression Regulation, Neoplastic Humans Male Mice Mice, Inbred BALB C Mice, Nude Neoplasm Invasiveness Prostatic Neoplasms - enzymology Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Serine Endopeptidases - biosynthesis Serine Endopeptidases - genetics Thymidine - metabolism Transfection Transplantation, Heterologous Up-Regulation
Online-Zugang:	Volltext
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