Ontogeny of Catecholamine and Adenosine Receptor-Mediated cAMP Signaling of Embryonic Red Blood Cells: Role of cGMP-Inhibited Phosphodiesterase 3 and Hemoglobin

We have previously shown that the cAMP signaling pathway controls major aspects of embryonic red blood cell (RBC) function in avian embryos (Glombitza et al, Am J Physiol 271:R973, 1996; and Dragon et al, Am J Physiol 271:R982, 1996) that are important for adaptation of the RBC gas transport propert...

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Veröffentlicht in:	Blood 1999-12, Vol.94 (12), p.4314-4320
Hauptverfasser:	Baumann, Rosemarie, Blass, Christian, Götz, Robert, Dragon, Stefanie
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-AMP Phosphodiesterases - metabolism Adenosine - pharmacology Animals Biological and medical sciences Catecholamines - pharmacology Cell differentiation, maturation, development, hematopoiesis Cell physiology Chick Embryo Cyclic AMP - metabolism Cyclic Nucleotide Phosphodiesterases, Type 3 Erythrocytes - metabolism Fundamental and applied biological sciences. Psychology Hemoglobins - metabolism Molecular and cellular biology Purinergic P1 Receptor Agonists Receptors, Purinergic P1 - metabolism Signal Transduction - drug effects
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