Ectopic Noggin Blocks Sensory and Nonsensory Organ Morphogenesis in the Chicken Inner Ear

Bone morphogenetic protein 4 (Bmp4) is expressed during multiple stages of development of the chicken inner ear. At the otocyst stage, Bmp4 is expressed in each presumptive sensory organ, as well as in the mesenchymal cells surrounding the region of the otocyst that is destined to form the semicircu...

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Veröffentlicht in:	Developmental biology 1999-12, Vol.216 (1), p.369-381
Hauptverfasser:	Chang, Weise, Nunes, Fabio D., De Jesus-Escobar, Jose M., Harland, Richard, Wu, Doris K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Avian Sarcoma Viruses - genetics Bone Morphogenetic Protein 4 bone morphogenetic proteins Bone Morphogenetic Proteins - genetics Bone Morphogenetic Proteins - metabolism Bromodeoxyuridine Carrier Proteins Chick Embryo chicks Drosophila Proteins Ear, Inner - embryology embryo (animal) Gene Expression Regulation, Developmental - drug effects Homeodomain Proteins - metabolism Immunohistochemistry In Situ Nick-End Labeling Insect Proteins - metabolism Morphogenesis - drug effects Msx1 MSX1 Transcription Factor N-Acetylglucosaminyltransferases p75NGFR Phenotype Proteins - genetics Proteins - pharmacology Receptors, Nerve Growth Factor - metabolism Semicircular Canals - embryology Space life sciences Transcription Factors Transfection TUNEL vestibule
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