In vitro and in vivo activities of cefpodoxime proxetil against penicillin-resistant Streptococcus pneumoniae

We evaluated in vitro and in vivo activities of cefpodoxime proxetil (CPDX-PR) in comparison with other oral beta-lactams, cefdinir (CFDN), cefditoren pivoxil (CDTR-PI), and faropenem (FRPM), against penicillin-susceptible and -resistant Streptococcus pneumoniae. In vitro activities (MICs) of CPDX,...

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Veröffentlicht in:	Japanese journal of antibiotics 1999-08, Vol.52 (8), p.533-540
Hauptverfasser:	Kawada, H, Kitayama, A, Fukuoka, T, Ishii, C, Abe, T, Kakuta, M, Domon, H, Ohya, S, Utsui, Y
Format:	Artikel
Sprache:	jpn
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology beta-Lactams Cefdinir Cefpodoxime Proxetil Ceftizoxime - analogs & derivatives Ceftizoxime - pharmacology Ceftizoxime - therapeutic use Cephalosporins - pharmacology Lactams Male Mice Microbial Sensitivity Tests Penicillin Resistance Pneumonia, Pneumococcal - drug therapy Prodrugs - pharmacology Prodrugs - therapeutic use Streptococcus pneumoniae - drug effects
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