The Role of BPH, Lower Urinary Tract Symptoms, and PSA Levels on Erectile Function of Brazilian Men Who Undergo Prostate Cancer Screening
Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common problems in middle-aged and older men. Recently, epidemiologic studies have shown significant associations between severity of LUTS and male sexual dysfunction. We analyzed the role of prostate enlargement, LUTS, and prosta...
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| Veröffentlicht in: | Journal of sexual medicine 2008-07, Vol.5 (7), p.1702-1707 |
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| creator | Antunes, Alberto A. Srougi, Miguel Dall'Oglio, Marcos F. Vicentini, Fabio Paranhos, Mario Freire, Geraldo C. |
| description | Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common problems in middle-aged and older men. Recently, epidemiologic studies have shown significant associations between severity of LUTS and male sexual dysfunction.
We analyzed the role of prostate enlargement, LUTS, and prostate specific antigen (PSA) levels in the erectile function of Brazilian men who underwent prostate cancer (PCa) screening.
We analyzed data from 1,008 consecutive patients enrolled in a PCa screening program. Benign prostatic hyperplasia (BPH) was defined as a prostate weight greater than 30g as defined by digital rectal examination. For statistical analysis, we used the chi-squared and analysis of variance tests. The odds ratios (OR) for correlation of ED with prostate volume LUTS and PSA were estimated using logistic regression models.
The American Urological Association (AUA) symptom score for LUTS and the International Index of Erectile Function.
Mean patient age was 61.2 years (45–87) and median PSA value was 1.9ng/mL. BPH was identified in 48.5% of patients. Mild, moderate, and severe LUTS were found in 52.3%, 30.9%, and 16.8% of cases, respectively. ED was classified as absent, mild, mild to moderate, moderate, and severe in 18.6%, 23.1%, 18.6%, 15.2%, and 24.5%, respectively. While only 5.4% of the patients with no ED presented severe LUTS, this finding was observed in 27.1% of patients with severe ED (P |
| doi_str_mv | 10.1111/j.1743-6109.2007.00713.x |
| format | Article |
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We analyzed the role of prostate enlargement, LUTS, and prostate specific antigen (PSA) levels in the erectile function of Brazilian men who underwent prostate cancer (PCa) screening.
We analyzed data from 1,008 consecutive patients enrolled in a PCa screening program. Benign prostatic hyperplasia (BPH) was defined as a prostate weight greater than 30g as defined by digital rectal examination. For statistical analysis, we used the chi-squared and analysis of variance tests. The odds ratios (OR) for correlation of ED with prostate volume LUTS and PSA were estimated using logistic regression models.
The American Urological Association (AUA) symptom score for LUTS and the International Index of Erectile Function.
Mean patient age was 61.2 years (45–87) and median PSA value was 1.9ng/mL. BPH was identified in 48.5% of patients. Mild, moderate, and severe LUTS were found in 52.3%, 30.9%, and 16.8% of cases, respectively. ED was classified as absent, mild, mild to moderate, moderate, and severe in 18.6%, 23.1%, 18.6%, 15.2%, and 24.5%, respectively. While only 5.4% of the patients with no ED presented severe LUTS, this finding was observed in 27.1% of patients with severe ED (P<0.001). Univariate logistic regression analysis demonstrated that age, prostate volume, AUA symptom score, and PSA levels were significant predictors of ED. However, when controlled for patient age, only LUTS remained as an independent predictor of ED.
Controlling for patient age, LUTS are independent risk factors for the development of ED among Brazilian men who undergo PCa screening. Antunes AA, Srougi M, Dall'Oglio MF, Vicentini F, Paranhos M, and Freire GC. The role of BPH, lower urinary tract symptoms, and PSA levels on erectile function of Brazilian men who undergo prostate cancer screening.</description><identifier>ISSN: 1743-6095</identifier><identifier>EISSN: 1743-6109</identifier><identifier>DOI: 10.1111/j.1743-6109.2007.00713.x</identifier><identifier>PMID: 18194186</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Benign Prostatic Hyperplasia ; Brazil - epidemiology ; Erectile Dysfunction ; Erectile Dysfunction - epidemiology ; Erectile Dysfunction - etiology ; Erectile Dysfunction - physiopathology ; Erectile Dysfunction - psychology ; Health Status Indicators ; Humans ; Logistic Models ; Lower Urinary Tract Symptoms ; Male ; Mass Screening ; Middle Aged ; Penile Erection ; Prospective Studies ; Prostate-Specific Antigen - blood ; Prostatic Hyperplasia - complications ; Prostatic Hyperplasia - immunology ; Prostatic Hyperplasia - physiopathology ; Prostatic Neoplasms - diagnosis ; Prostatic Neoplasms - prevention & control ; Risk Factors ; Urination Disorders - diagnosis ; Urination Disorders - physiopathology ; Urodynamics</subject><ispartof>Journal of sexual medicine, 2008-07, Vol.5 (7), p.1702-1707</ispartof><rights>2010 International Society for Sexual Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-6aec43ee7771807e6257552b60fd5f434ee70976cd7b73425e8a9843cf2aab4e3</citedby><cites>FETCH-LOGICAL-c372t-6aec43ee7771807e6257552b60fd5f434ee70976cd7b73425e8a9843cf2aab4e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18194186$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Antunes, Alberto A.</creatorcontrib><creatorcontrib>Srougi, Miguel</creatorcontrib><creatorcontrib>Dall'Oglio, Marcos F.</creatorcontrib><creatorcontrib>Vicentini, Fabio</creatorcontrib><creatorcontrib>Paranhos, Mario</creatorcontrib><creatorcontrib>Freire, Geraldo C.</creatorcontrib><title>The Role of BPH, Lower Urinary Tract Symptoms, and PSA Levels on Erectile Function of Brazilian Men Who Undergo Prostate Cancer Screening</title><title>Journal of sexual medicine</title><addtitle>J Sex Med</addtitle><description>Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common problems in middle-aged and older men. Recently, epidemiologic studies have shown significant associations between severity of LUTS and male sexual dysfunction.
We analyzed the role of prostate enlargement, LUTS, and prostate specific antigen (PSA) levels in the erectile function of Brazilian men who underwent prostate cancer (PCa) screening.
We analyzed data from 1,008 consecutive patients enrolled in a PCa screening program. Benign prostatic hyperplasia (BPH) was defined as a prostate weight greater than 30g as defined by digital rectal examination. For statistical analysis, we used the chi-squared and analysis of variance tests. The odds ratios (OR) for correlation of ED with prostate volume LUTS and PSA were estimated using logistic regression models.
The American Urological Association (AUA) symptom score for LUTS and the International Index of Erectile Function.
Mean patient age was 61.2 years (45–87) and median PSA value was 1.9ng/mL. BPH was identified in 48.5% of patients. Mild, moderate, and severe LUTS were found in 52.3%, 30.9%, and 16.8% of cases, respectively. ED was classified as absent, mild, mild to moderate, moderate, and severe in 18.6%, 23.1%, 18.6%, 15.2%, and 24.5%, respectively. While only 5.4% of the patients with no ED presented severe LUTS, this finding was observed in 27.1% of patients with severe ED (P<0.001). Univariate logistic regression analysis demonstrated that age, prostate volume, AUA symptom score, and PSA levels were significant predictors of ED. However, when controlled for patient age, only LUTS remained as an independent predictor of ED.
Controlling for patient age, LUTS are independent risk factors for the development of ED among Brazilian men who undergo PCa screening. Antunes AA, Srougi M, Dall'Oglio MF, Vicentini F, Paranhos M, and Freire GC. The role of BPH, lower urinary tract symptoms, and PSA levels on erectile function of Brazilian men who undergo prostate cancer screening.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Benign Prostatic Hyperplasia</subject><subject>Brazil - epidemiology</subject><subject>Erectile Dysfunction</subject><subject>Erectile Dysfunction - epidemiology</subject><subject>Erectile Dysfunction - etiology</subject><subject>Erectile Dysfunction - physiopathology</subject><subject>Erectile Dysfunction - psychology</subject><subject>Health Status Indicators</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Lower Urinary Tract Symptoms</subject><subject>Male</subject><subject>Mass Screening</subject><subject>Middle Aged</subject><subject>Penile Erection</subject><subject>Prospective Studies</subject><subject>Prostate-Specific Antigen - blood</subject><subject>Prostatic Hyperplasia - complications</subject><subject>Prostatic Hyperplasia - immunology</subject><subject>Prostatic Hyperplasia - physiopathology</subject><subject>Prostatic Neoplasms - diagnosis</subject><subject>Prostatic Neoplasms - prevention & control</subject><subject>Risk Factors</subject><subject>Urination Disorders - diagnosis</subject><subject>Urination Disorders - physiopathology</subject><subject>Urodynamics</subject><issn>1743-6095</issn><issn>1743-6109</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkVFv0zAQxy0EYmPwFdA98bRmduzEyeNWbWxSJ6q1FY-W61w2V4ld7HRsfAO-Nc5a4HEnWT75_vc_63eEAKMZS3G2yZgUfFIyWmc5pTJLh_Hs6Q05_ld4-zendXFEPsS4oZSnyN-TI1axWrCqPCa_lw8Id75D8C1czK9PYeZ_YoBVsE6HZ1gGbQZYPPfbwffxFLRrYL44hxk-YhfBO7gMaAabDK52LiXpZXQK-pftrHZwiw6-P3hYuQbDvYd58HHQA8JUO5MGLUxAdNbdfyTvWt1F_HS4T8jq6nI5vZ7Mvn29mZ7PJobLfJiUGo3giFJKVlGJZV7IosjXJW2bohVcpBKtZWkauZZc5AVWuq4EN22u9VogPyFf9r7b4H_sMA6qt9Fg12mHfhdVWXMuqqJMwmovNOnLMWCrtsH2CYpiVI1rUBs1ElYjbTWuQb2sQT2l1s-HGbt1j83_xgP3JLjYCxJEfLQYVDQWE5DGjjhV4-3rU_4AJFeZCw</recordid><startdate>20080701</startdate><enddate>20080701</enddate><creator>Antunes, Alberto A.</creator><creator>Srougi, Miguel</creator><creator>Dall'Oglio, Marcos F.</creator><creator>Vicentini, Fabio</creator><creator>Paranhos, Mario</creator><creator>Freire, Geraldo C.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080701</creationdate><title>The Role of BPH, Lower Urinary Tract Symptoms, and PSA Levels on Erectile Function of Brazilian Men Who Undergo Prostate Cancer Screening</title><author>Antunes, Alberto A. ; Srougi, Miguel ; Dall'Oglio, Marcos F. ; Vicentini, Fabio ; Paranhos, Mario ; Freire, Geraldo C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-6aec43ee7771807e6257552b60fd5f434ee70976cd7b73425e8a9843cf2aab4e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Benign Prostatic Hyperplasia</topic><topic>Brazil - epidemiology</topic><topic>Erectile Dysfunction</topic><topic>Erectile Dysfunction - epidemiology</topic><topic>Erectile Dysfunction - etiology</topic><topic>Erectile Dysfunction - physiopathology</topic><topic>Erectile Dysfunction - psychology</topic><topic>Health Status Indicators</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Lower Urinary Tract Symptoms</topic><topic>Male</topic><topic>Mass Screening</topic><topic>Middle Aged</topic><topic>Penile Erection</topic><topic>Prospective Studies</topic><topic>Prostate-Specific Antigen - blood</topic><topic>Prostatic Hyperplasia - complications</topic><topic>Prostatic Hyperplasia - immunology</topic><topic>Prostatic Hyperplasia - physiopathology</topic><topic>Prostatic Neoplasms - diagnosis</topic><topic>Prostatic Neoplasms - prevention & control</topic><topic>Risk Factors</topic><topic>Urination Disorders - diagnosis</topic><topic>Urination Disorders - physiopathology</topic><topic>Urodynamics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Antunes, Alberto A.</creatorcontrib><creatorcontrib>Srougi, Miguel</creatorcontrib><creatorcontrib>Dall'Oglio, Marcos F.</creatorcontrib><creatorcontrib>Vicentini, Fabio</creatorcontrib><creatorcontrib>Paranhos, Mario</creatorcontrib><creatorcontrib>Freire, Geraldo C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of sexual medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Antunes, Alberto A.</au><au>Srougi, Miguel</au><au>Dall'Oglio, Marcos F.</au><au>Vicentini, Fabio</au><au>Paranhos, Mario</au><au>Freire, Geraldo C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Role of BPH, Lower Urinary Tract Symptoms, and PSA Levels on Erectile Function of Brazilian Men Who Undergo Prostate Cancer Screening</atitle><jtitle>Journal of sexual medicine</jtitle><addtitle>J Sex Med</addtitle><date>2008-07-01</date><risdate>2008</risdate><volume>5</volume><issue>7</issue><spage>1702</spage><epage>1707</epage><pages>1702-1707</pages><issn>1743-6095</issn><eissn>1743-6109</eissn><abstract>Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common problems in middle-aged and older men. Recently, epidemiologic studies have shown significant associations between severity of LUTS and male sexual dysfunction.
We analyzed the role of prostate enlargement, LUTS, and prostate specific antigen (PSA) levels in the erectile function of Brazilian men who underwent prostate cancer (PCa) screening.
We analyzed data from 1,008 consecutive patients enrolled in a PCa screening program. Benign prostatic hyperplasia (BPH) was defined as a prostate weight greater than 30g as defined by digital rectal examination. For statistical analysis, we used the chi-squared and analysis of variance tests. The odds ratios (OR) for correlation of ED with prostate volume LUTS and PSA were estimated using logistic regression models.
The American Urological Association (AUA) symptom score for LUTS and the International Index of Erectile Function.
Mean patient age was 61.2 years (45–87) and median PSA value was 1.9ng/mL. BPH was identified in 48.5% of patients. Mild, moderate, and severe LUTS were found in 52.3%, 30.9%, and 16.8% of cases, respectively. ED was classified as absent, mild, mild to moderate, moderate, and severe in 18.6%, 23.1%, 18.6%, 15.2%, and 24.5%, respectively. While only 5.4% of the patients with no ED presented severe LUTS, this finding was observed in 27.1% of patients with severe ED (P<0.001). Univariate logistic regression analysis demonstrated that age, prostate volume, AUA symptom score, and PSA levels were significant predictors of ED. However, when controlled for patient age, only LUTS remained as an independent predictor of ED.
Controlling for patient age, LUTS are independent risk factors for the development of ED among Brazilian men who undergo PCa screening. Antunes AA, Srougi M, Dall'Oglio MF, Vicentini F, Paranhos M, and Freire GC. The role of BPH, lower urinary tract symptoms, and PSA levels on erectile function of Brazilian men who undergo prostate cancer screening.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>18194186</pmid><doi>10.1111/j.1743-6109.2007.00713.x</doi><tpages>6</tpages></addata></record> |
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| subjects | Aged Aged, 80 and over Benign Prostatic Hyperplasia Brazil - epidemiology Erectile Dysfunction Erectile Dysfunction - epidemiology Erectile Dysfunction - etiology Erectile Dysfunction - physiopathology Erectile Dysfunction - psychology Health Status Indicators Humans Logistic Models Lower Urinary Tract Symptoms Male Mass Screening Middle Aged Penile Erection Prospective Studies Prostate-Specific Antigen - blood Prostatic Hyperplasia - complications Prostatic Hyperplasia - immunology Prostatic Hyperplasia - physiopathology Prostatic Neoplasms - diagnosis Prostatic Neoplasms - prevention & control Risk Factors Urination Disorders - diagnosis Urination Disorders - physiopathology Urodynamics |
| title | The Role of BPH, Lower Urinary Tract Symptoms, and PSA Levels on Erectile Function of Brazilian Men Who Undergo Prostate Cancer Screening |
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