Induction of immune tolerance with recombinant factor VIII in haemophilia A patients with inhibitors

We report on 11 patients (nine unrelated and a brother pair) with severe haemophilia A and factor VIII (FVIII) inhibitor, in whom immune tolerance (IIT) was induced with recombinant FVIII (r‐FVIII). Their age ranged from 11 months to 47 years. The number of exposure days (ED) at inhibitor detection...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Haemophilia : the official journal of the World Federation of Hemophilia 1999-11, Vol.5 (6), p.431-435
Hauptverfasser:	Batlle, J, Lopez, M F, Brackmann, H H, Gaillard, S, Goudemand, J, Humbert, J, De Moerloose, P, Maass, E, Mauz-Körholz, C, Sultan, Y, Stieltjes, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Child, Preschool Europe Factor VIII - administration & dosage FVIII FVIII antibodies Hemophilia A - drug therapy Hemophilia A - immunology Humans immune tolerance Immune Tolerance - drug effects Infant Isoantigens - blood Isoantigens - drug effects Middle Aged recombinant FVIII Recombinant Proteins - administration & dosage Surveys and Questionnaires Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!