Kinetics of in vitro release of a model nucleoside deoxyuridine from crosslinked insoluble collagen and collagen–gelatin microspheres

The objective of this research is to investigate the effect of highly crosslinked insoluble collagen and collagen–gelatin hybrid matrices as platforms for controlled release of a highly water soluble model nucleoside, deoxyuridine as well as a high molecular weight model compound fluoroscienisothoic...

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Veröffentlicht in:	International journal of pharmaceutics 1999-12, Vol.193 (1), p.113-122
Hauptverfasser:	Chowdhury, Dipak K., Mitra, Ashim K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Collagen - chemistry Collagen and gelatin microspheres Controlled release Cross-Linking Reagents - chemistry Delayed-Action Preparations Deoxyuridine Deoxyuridine - pharmacokinetics Dextrans - pharmacokinetics Diffusion FITC-dextran Fluorescein-5-isothiocyanate - analogs & derivatives Fluorescein-5-isothiocyanate - pharmacokinetics Gelatin - chemistry General pharmacology In Vitro Techniques Medical sciences Microencapsulation Microspheres Models, Theoretical Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Solubility Time Factors
Online-Zugang:	Volltext
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