An internal ribosome entry site mediates the initiation of soluble guanylyl cyclase beta2 mRNA translation

The soluble guanylyl cyclases (sGC), the receptor for nitric oxide, are heterodimers consisting of an alpha- and beta-subunit. This study aimed to investigate the translational mechanism of the sGC beta2-subunit. Two mRNA species for sGC beta2 were isolated from human kidney. These transcripts had d...

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Veröffentlicht in:	The FEBS journal 2008-07, Vol.275 (14), p.3598-3607
Hauptverfasser:	Vazquez-Padron, Roberto I, Pham, Si M, Mateu, Dania, Khan, Sheik, Aitouche, Abdelouahab
Format:	Artikel
Sprache:	eng
Schlagworte:	5' Untranslated Regions - chemistry 5' Untranslated Regions - genetics Animals Base Sequence Cell Line Cloning, Molecular Genes, Reporter Guanylate Cyclase - biosynthesis Guanylate Cyclase - genetics HeLa Cells Humans Molecular Sequence Data Nucleic Acid Conformation Peptide Chain Initiation, Translational Promoter Regions, Genetic Receptors, Cytoplasmic and Nuclear - biosynthesis Receptors, Cytoplasmic and Nuclear - genetics RNA Splice Sites Soluble Guanylyl Cyclase Transcription, Genetic
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