The genetic variability of the VH genes in follicular lymphoma: the impact of the hypermutation mechanism

Follicular lymphoma (FL) cells have inherited an activated hypermutation mechanism from their origin of germinal centre B cells. Based on today's knowledge of the intrinsic properties related to this mechanism and the VH base composition, reconsideration of previous reports should be made on a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of haematology 1999-12, Vol.107 (3), p.625-640
Hauptverfasser:	Noppe, Sofie M., Heirman, Carlo, Bakkus, Marleen H. C., Brissinck, Jan, Schots, Rik, Thielemans, Kris
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Biological and medical sciences deletions DNA Transposable Elements - genetics follicular lymphoma Gene Deletion Genes, Immunoglobulin - genetics Hematologic and hematopoietic diseases Humans hypermutation insertions Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Follicular - genetics Medical sciences Mutation - genetics VH genes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!