Microsomal Prostaglandin E2 Synthase-1 (mPGES-1): A Novel Anti-Inflammatory Therapeutic Target
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| Veröffentlicht in: | Journal of medicinal chemistry 2008-07, Vol.51 (14), p.4059-4067 |
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| container_end_page | 4067 |
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| container_issue | 14 |
| container_start_page | 4059 |
| container_title | Journal of medicinal chemistry |
| container_volume | 51 |
| creator | Friesen, Richard W Mancini, Joseph A |
| description | |
| doi_str_mv | 10.1021/jm800197b |
| format | Article |
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Antiinflammatory agents ; Fever - enzymology ; Humans ; Intramolecular Oxidoreductases - drug effects ; Intramolecular Oxidoreductases - metabolism ; Medical sciences ; Mice ; Mice, Knockout ; Microsomes - enzymology ; Pain - enzymology ; Pharmacology. 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Med. Chem</addtitle><subject>Animals</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</subject><subject>Atherosclerosis - enzymology</subject><subject>Biological and medical sciences</subject><subject>Bones, joints and connective tissue. Antiinflammatory agents</subject><subject>Fever - enzymology</subject><subject>Humans</subject><subject>Intramolecular Oxidoreductases - drug effects</subject><subject>Intramolecular Oxidoreductases - metabolism</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Mice, Knockout</subject><subject>Microsomes - enzymology</subject><subject>Pain - enzymology</subject><subject>Pharmacology. Drug treatments</subject><subject>Prostaglandin-E Synthases</subject><subject>Stroke - enzymology</subject><issn>0022-2623</issn><issn>1520-4804</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkU9vEzEQxS1ERUPhwBdAvoDg4GKP7V1vb6GEtqKUSAlXrFmvt92wf4LtReTbs7RpOM1I85snvfcIeSX4qeAgPmw6w7ko8vIJmQkNnCnD1VMy4xyAQQbymDyPccM5lwLkM3IsjNJFrosZ-fG1cWGIQ4ctXU5LwtsW-6rp6QLoatenO4yeCfquW14sVky8P6NzejP89i2d96lhV33dYtdhGsKOru98wK0fU-PoGsOtTy_IUY1t9C_384R8_7xYn1-y628XV-fza4ZgTGJVrXxVc65VlkvQJXiFUJWoM1c7yL2syqL0oEG6IqsrNN6YAsX0UueFUEqekLcPutsw_Bp9TLZrovPt5MUPY7RZIUHqe_D1HhzLzld2G5oOw84-JjIBb_YARodtHbB3TTxwwLXQWpuJYw9cE5P_c7hj-GknD7m26-XK6i_ZR7i8UfbTf1100W6GMfRTHlZw-69Be2hQ_gU4GoiL</recordid><startdate>20080724</startdate><enddate>20080724</enddate><creator>Friesen, Richard W</creator><creator>Mancini, Joseph A</creator><general>American Chemical Society</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20080724</creationdate><title>Microsomal Prostaglandin E2 Synthase-1 (mPGES-1): A Novel Anti-Inflammatory Therapeutic Target</title><author>Friesen, Richard W ; Mancini, Joseph A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a288t-df4edf005467325b2e4a2dba56cfc27e3db9be2523c96fda8e889a1df0f791443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Animals</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - pharmacology</topic><topic>Atherosclerosis - enzymology</topic><topic>Biological and medical sciences</topic><topic>Bones, joints and connective tissue. Antiinflammatory agents</topic><topic>Fever - enzymology</topic><topic>Humans</topic><topic>Intramolecular Oxidoreductases - drug effects</topic><topic>Intramolecular Oxidoreductases - metabolism</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Mice, Knockout</topic><topic>Microsomes - enzymology</topic><topic>Pain - enzymology</topic><topic>Pharmacology. 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| fulltext | fulltext |
| identifier | ISSN: 0022-2623 |
| ispartof | Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4059-4067 |
| issn | 0022-2623 1520-4804 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69323544 |
| source | ACS Publications; MEDLINE |
| subjects | Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology Atherosclerosis - enzymology Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Fever - enzymology Humans Intramolecular Oxidoreductases - drug effects Intramolecular Oxidoreductases - metabolism Medical sciences Mice Mice, Knockout Microsomes - enzymology Pain - enzymology Pharmacology. Drug treatments Prostaglandin-E Synthases Stroke - enzymology |
| title | Microsomal Prostaglandin E2 Synthase-1 (mPGES-1): A Novel Anti-Inflammatory Therapeutic Target |
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