Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate

Background & Aims: Hepatitis C virus (HCV) is a leading cause of chronic hepatitis in the world. Successful vaccine development is crucial in controlling global HCV infection. We have previously described the generation of HCV-like particles (HCV-LPs) in insect cells using a recombinant baculovi...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 1999-12, Vol.117 (6), p.1397-1407
Hauptverfasser:	Baumert, Thomas F., Vergalla, John, Satoi, Jujin, Thomson, Michael, Lechmann, Martin, Herion, David, Greenberg, Harry B., Ito, Susumu, Liang, T.Jake
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cells, Cultured Enzyme-Linked Immunosorbent Assay Epidemiology. Vaccinations General aspects Glycosylation Hepacivirus - genetics Hepacivirus - immunology Hepacivirus - metabolism Infectious diseases Insecta Medical sciences Vaccines, Synthetic - genetics Viral Envelope Proteins - analysis Viral Hepatitis Vaccines - genetics Viral Structural Proteins - analysis Virus Replication
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