Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial

Summary Background Observational epidemiological studies have shown a positive association between hypertension and risk of incident dementia; however, the effects of antihypertensive therapy on cognitive function in controlled trials have been conflicting, and meta-analyses of the trials have not p...

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Veröffentlicht in:	Lancet neurology 2008-08, Vol.7 (8), p.683-689
Hauptverfasser:	Peters, Ruth, PhD, Beckett, Nigel, MBchB, Forette, Francoise, MD, Tuomilehto, Jaakko, MD, Clarke, Robert, FRCP, Ritchie, Craig, MRCPsych, Waldman, Adam, PhD, Walton, Ivan, FRCP, Poulter, Ruth, BSc, Ma, Shuping, MD, Comsa, Marius, MD, Burch, Lisa, BSc, Fletcher, Astrid, PhD, Bulpitt, Christopher, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged, 80 and over Alzheimer's disease Antihypertensive Agents - therapeutic use Blood pressure Blood Pressure - drug effects Cognition - drug effects Dementia Dementia - epidemiology Dementia - prevention & control Double-Blind Method Female Geriatric Assessment Humans Hypertension - drug therapy Hypertension - epidemiology Incidence Indapamide - therapeutic use Longitudinal Studies Male Mental Status Schedule Neurology Neuropsychological Tests Older people Perindopril - therapeutic use Systematic review
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