Cell lineage analysis of a mouse tumor

Revealing the lineage relations among cancer cells can shed light on tumor growth patterns and metastasis formation, yet cell lineages have been difficult to come by in the absence of a suitable method. We previously developed a method for reconstructing cell lineage trees from genomic variability c...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2008-07, Vol.68 (14), p.5924-5931
Hauptverfasser:	Frumkin, Dan, Wasserstrom, Adam, Itzkovitz, Shalev, Stern, Tomer, Harmelin, Alon, Eilam, Raya, Rechavi, Gideon, Shapiro, Ehud
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Animals Cell Lineage Cell Proliferation Disease Progression DNA Mutational Analysis Genotype Heterozygote Lymphoma - genetics Lymphoma - pathology Mice Mice, Inbred C57BL Models, Biological Mutation MutL Protein Homolog 1 Neoplasms - genetics Neoplasms - pathology Nuclear Proteins - genetics Phylogeny
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