Microarray design using virtual hybridization to study variations in REP-CMT1A sites

Gene PMP22 is duplicated in patients with CMT1A. Duplication is due to an unequal chromatid interchange during meiosis that takes place between two 24 Kb regions named REP-CMT1A proximal and distal sites. Homology is approximately 98%. Within each one of the sites we find zones termed hot spots wher...

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Veröffentlicht in:	Gaceta médica de México 2008-01, Vol.144 (1), p.1-6
Hauptverfasser:	Hernández-Zamora, Edgar, Arenas-Sordo, María de la Luz, Maldonado-Rodríguez, Rogelio
Format:	Artikel
Sprache:	spa
Schlagworte:	Charcot-Marie-Tooth Disease - genetics Humans Myelin Proteins - genetics Oligonucleotide Array Sequence Analysis - methods Proteins - genetics
Online-Zugang:	Volltext
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