Review article: current antiviral therapy of chronic hepatitis B

Summary Background The long‐term goals of therapy for chronic hepatitis B are to reduce serum HBV DNA to low or undetectable levels and ultimately reduce or prevent the development of cirrhosis and hepatocellular carcinoma. Aim To review the current treatment of chronic hepatitis B, with a focus o...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2008-07, Vol.28 (2), p.167-177
Hauptverfasser:	AYOUB, W. S., KEEFFE, E. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - therapeutic use Antiviral Agents - therapeutic use Biological and medical sciences Carcinoma, Hepatocellular - prevention & control Deoxycytidine - analogs & derivatives Deoxycytidine - therapeutic use Digestive system Drug Resistance, Viral Emtricitabine Gastroenterology. Liver. Pancreas. Abdomen Guanine - analogs & derivatives Guanine - therapeutic use Hepatitis B virus Hepatitis B virus - physiology Hepatitis B, Chronic - diagnosis Hepatitis B, Chronic - drug therapy Human viral diseases Humans Infectious diseases Interferon-alpha - therapeutic use Lamivudine - therapeutic use Liver Cirrhosis - prevention & control Medical sciences Nucleosides - therapeutic use Organophosphonates - therapeutic use Pharmacology. Drug treatments Polyethylene Glycols - therapeutic use Pyrimidinones - therapeutic use Recombinant Proteins Reverse Transcriptase Inhibitors - therapeutic use Tenofovir Thymidine - analogs & derivatives Viral diseases Viral hepatitis Virus Replication
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