Ceramide concentrations in septic patients: A possible marker of multiple organ dysfunction syndrome

OBJECTIVES:To investigate the concentrations of mononuclear cell-associated ceramide and serum tumor necrosis factor-α (TNF-α) in patients with sepsis and to assess their predictive value for the development of multiple organ dysfunction syndrome (MODS). DESIGN:Prospective, cohort study. SETTING:Int...

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Veröffentlicht in:	Critical care medicine 1999-11, Vol.27 (11), p.2413-2417
Hauptverfasser:	Delogu, Giovanna, Famularo, Giuseppe, Amati, Fabrizio, Signore, Luciano, Antonucci, Adriana, Trinchieri, Vito, Di Marzio, Luisa, Cifone, Maria Grazia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Apoptosis Biological and medical sciences Biomarkers - blood Ceramides - blood Disease Progression Emergency and intensive care: infection, septic shock Female Follow-Up Studies Hospitals, University Humans Intensive care medicine Intensive Care Units Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - pathology Male Medical sciences Middle Aged Multiple Organ Failure - blood Multiple Organ Failure - diagnosis Multiple Organ Failure - etiology Prognosis Prospective Studies ROC Curve Sepsis - blood Sepsis - complications Sepsis - diagnosis Tumor Necrosis Factor-alpha - metabolism
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