Effects of apoptosis and lipid peroxidation on T‐lymphoblastoid phospholipid‐dependent procoagulant activity

Background: Coagulation has an absolute requirement for macromolecular complexes to be assembled on a negatively charged phospholipid (PL) surface. Previously, we reported that malignant T‐lymphoblastoid cells have the ability to support procoagulant activity (PCA) independently of tissue factor by...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2008-07, Vol.6 (7), p.1122-1130
Hauptverfasser:	PICKERING, W., GRAY, E., GOODALL, A. H., BARROWCLIFFE, T. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin A5 - analysis Apoptosis Cell Line Flow Cytometry Humans Lipid Peroxidation Neoplasms - blood Neoplasms - complications Oxidative Stress Phosphatidylserines - analysis phospholipid procoagulant activity T-Lymphocytes - pathology Thrombin - biosynthesis Thrombophilia - etiology T cells
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