Antigen-Experienced T Cells Undergo a Transient Phase of Unresponsiveness Following Optimal Stimulation

Interaction of the Ag-specific receptor of T lymphocytes with its Ag/MHC ligand can lead either to cell activation or to a state of unresponsiveness often referred to as anergy. It has been generally assumed that anergy develops as a consequence of inadequate stimulation, such as in response to alte...

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Veröffentlicht in:The Journal of immunology (1950) 1999-12, Vol.163 (11), p.5929-5936
Hauptverfasser: De Mattia, Fabrizio, Chomez, Susanna, Van Laethem, Francois, Moulin, Veronique, Urbain, Jacques, Moser, Muriel, Leo, Oberdan, Andris, Fabienne
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Sprache:eng
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