FTO gene associates to metabolic syndrome in women with polycystic ovary syndrome

The FTO ( Fat mass and obesity associated) locus has recently been associated with obesity and type 2 diabetes (T2D) in humans. To understand the role of the FTO gene in polycystic ovary syndrome (PCOS) we genotyped single nucleotide polymorphism (SNP) rs1421085 (C/T) in women with PCOS ( n = 207) a...

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Veröffentlicht in:	Biochemical and biophysical research communications 2008-08, Vol.373 (2), p.230-234
Hauptverfasser:	Attaoua, Redha, Ait El Mkadem, Samira, Radian, Serban, Fica, Simona, Hanzu, Felicia, Albu, Alice, Gheorghiu, Monica, Coculescu, Mihai, Grigorescu, Florin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alpha-Ketoglutarate-Dependent Dioxygenase FTO Body Mass Index Case-Control Studies Fasting Female FTO gene Genetic association Genotype Glucose - metabolism Glucose intolerance Glucose Intolerance - complications Glucose Intolerance - genetics Haplotype Homozygote Humans Insulin resistance Metabolic syndrome Metabolic Syndrome - complications Metabolic Syndrome - genetics Obesity Phenotype Polycystic ovary Polycystic Ovary Syndrome - complications Polycystic Ovary Syndrome - genetics Polymorphism, Single Nucleotide Proteins - genetics Single nucleotide polymorphism
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