An investigation into the use of micro-thermal analysis for the solid state characterisation of an HPMC tablet formulation

The use of micro-thermal analysis (μTA™) as a novel means of differentiating between components in a model tablet formulation is described. This technique involves a modification of atomic force microscopy (AFM) such that the standard AFM tip is replaced with a Wollaston wire, thereby allowing the p...

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Veröffentlicht in:International journal of pharmaceutics 1999-12, Vol.192 (1), p.97-103
Hauptverfasser: Royall, Paul G, Craig, Duncan Q.M, Price, Duncan M, Reading, Mike, Lever, Trevor J
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Sprache:eng
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