Innate and Adaptive Immune Responses Co-operate to Protect Cattle against Theileria annulata
For many years it was assumed that Theileria annulata resembled T. parva, parasitizing lymphocytes and causing lymphoproliferative disease, with the two species being controlled by similar protective immune responses. Patricia Preston et al. here review the evidence that has led to a different view...
Gespeichert in:
| Veröffentlicht in: | Parasitology Today 1999-07, Vol.15 (7), p.268-274 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 274 |
|---|---|
| container_issue | 7 |
| container_start_page | 268 |
| container_title | Parasitology Today |
| container_volume | 15 |
| creator | Preston, P.M. Hall, F.R. Glass, E.J. Campbell, J.D.M. Darghouth, M.A. Ahmed, J.S. Shiels, B.R. Spooner, R.L. Jongejan, F. Brown, C.G.D. |
| description | For many years it was assumed that Theileria annulata resembled T. parva, parasitizing lymphocytes and causing lymphoproliferative disease, with the two species being controlled by similar protective immune responses. Patricia Preston et al. here review the evidence that has led to a different view of T. annulata. It is now thought that the schizonts of T. annulata inhabit macrophages and B cells, and that tropical theileriosis is not a lymphoproliferative disease. Both innate and adaptive responses contribute to recovery from infection and resistance to challenge and cytokines produced by infected and uninfected cells influence the outcome of infection. Partial protection has been stimulated recently by defined recombinant antigens; efficacy depended upon the delivery system. |
| doi_str_mv | 10.1016/S0169-4758(99)01466-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69297423</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0169475899014660</els_id><sourcerecordid>69297423</sourcerecordid><originalsourceid>FETCH-LOGICAL-c392t-96e1012af20ffb36b8c409324c929afc9dac725c177b831c50ccf455b20dfc8a3</originalsourceid><addsrcrecordid>eNqFkMtKxDAUhrNQHG-PoHQluqjm0jbNSmTwMiAoOu6EkKanGmmTmqSCb2_GEXHn5gQO3_8f8iF0QPApwaQ6e0xD5AUv62MhTjApqirHG2j7dz1DOyG8YYw5Z8UWmhHMOC9pvY2eF9aqCJmybXbRqjGaD8gWwzBZyB4gjM4GCNnc5W4EvwKjy-69i6BjNlcx9in6oowNMVu-gunBG5XK7NSrqPbQZqf6APs_7y56urpczm_y27vrxfziNtdM0JiLCtI3qOoo7rqGVU2tCywYLbSgQnVatEpzWmrCeVMzokusdVeUZUNx2-lasV10tO4dvXufIEQ5mKCh75UFNwVZpR5eUPYvSDgjpCpXYLkGtXcheOjk6M2g_KckWK6cy2_nciVXCiG_nUuccoc_B6ZmgPZPai08AedrAJKPDwNeBm3AamiNT05l68w_J74AyLWTjA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17311653</pqid></control><display><type>article</type><title>Innate and Adaptive Immune Responses Co-operate to Protect Cattle against Theileria annulata</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Preston, P.M. ; Hall, F.R. ; Glass, E.J. ; Campbell, J.D.M. ; Darghouth, M.A. ; Ahmed, J.S. ; Shiels, B.R. ; Spooner, R.L. ; Jongejan, F. ; Brown, C.G.D.</creator><creatorcontrib>Preston, P.M. ; Hall, F.R. ; Glass, E.J. ; Campbell, J.D.M. ; Darghouth, M.A. ; Ahmed, J.S. ; Shiels, B.R. ; Spooner, R.L. ; Jongejan, F. ; Brown, C.G.D.</creatorcontrib><description>For many years it was assumed that Theileria annulata resembled T. parva, parasitizing lymphocytes and causing lymphoproliferative disease, with the two species being controlled by similar protective immune responses. Patricia Preston et al. here review the evidence that has led to a different view of T. annulata. It is now thought that the schizonts of T. annulata inhabit macrophages and B cells, and that tropical theileriosis is not a lymphoproliferative disease. Both innate and adaptive responses contribute to recovery from infection and resistance to challenge and cytokines produced by infected and uninfected cells influence the outcome of infection. Partial protection has been stimulated recently by defined recombinant antigens; efficacy depended upon the delivery system.</description><identifier>ISSN: 0169-4758</identifier><identifier>DOI: 10.1016/S0169-4758(99)01466-0</identifier><identifier>PMID: 10377528</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>Adaptive responses ; Animals ; Antigens, Protozoan - immunology ; Cattle ; Cytokines - metabolism ; Host-Parasite Interactions - immunology ; Immunity ; Innate responses ; Leukocytes, Mononuclear - metabolism ; Leukocytes, Mononuclear - parasitology ; Macrophages - parasitology ; Protective immunity ; Protozoan Vaccines - immunology ; Theileria annulata ; Theileria annulata - immunology ; Theileria annulata - physiology ; Theileriasis - immunology ; Vaccines, Synthetic - immunology</subject><ispartof>Parasitology Today, 1999-07, Vol.15 (7), p.268-274</ispartof><rights>1999 Elsevier Science Ltd</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c392t-96e1012af20ffb36b8c409324c929afc9dac725c177b831c50ccf455b20dfc8a3</citedby><cites>FETCH-LOGICAL-c392t-96e1012af20ffb36b8c409324c929afc9dac725c177b831c50ccf455b20dfc8a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>313,314,780,784,792,27922,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10377528$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Preston, P.M.</creatorcontrib><creatorcontrib>Hall, F.R.</creatorcontrib><creatorcontrib>Glass, E.J.</creatorcontrib><creatorcontrib>Campbell, J.D.M.</creatorcontrib><creatorcontrib>Darghouth, M.A.</creatorcontrib><creatorcontrib>Ahmed, J.S.</creatorcontrib><creatorcontrib>Shiels, B.R.</creatorcontrib><creatorcontrib>Spooner, R.L.</creatorcontrib><creatorcontrib>Jongejan, F.</creatorcontrib><creatorcontrib>Brown, C.G.D.</creatorcontrib><title>Innate and Adaptive Immune Responses Co-operate to Protect Cattle against Theileria annulata</title><title>Parasitology Today</title><addtitle>Parasitol Today</addtitle><description>For many years it was assumed that Theileria annulata resembled T. parva, parasitizing lymphocytes and causing lymphoproliferative disease, with the two species being controlled by similar protective immune responses. Patricia Preston et al. here review the evidence that has led to a different view of T. annulata. It is now thought that the schizonts of T. annulata inhabit macrophages and B cells, and that tropical theileriosis is not a lymphoproliferative disease. Both innate and adaptive responses contribute to recovery from infection and resistance to challenge and cytokines produced by infected and uninfected cells influence the outcome of infection. Partial protection has been stimulated recently by defined recombinant antigens; efficacy depended upon the delivery system.</description><subject>Adaptive responses</subject><subject>Animals</subject><subject>Antigens, Protozoan - immunology</subject><subject>Cattle</subject><subject>Cytokines - metabolism</subject><subject>Host-Parasite Interactions - immunology</subject><subject>Immunity</subject><subject>Innate responses</subject><subject>Leukocytes, Mononuclear - metabolism</subject><subject>Leukocytes, Mononuclear - parasitology</subject><subject>Macrophages - parasitology</subject><subject>Protective immunity</subject><subject>Protozoan Vaccines - immunology</subject><subject>Theileria annulata</subject><subject>Theileria annulata - immunology</subject><subject>Theileria annulata - physiology</subject><subject>Theileriasis - immunology</subject><subject>Vaccines, Synthetic - immunology</subject><issn>0169-4758</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtKxDAUhrNQHG-PoHQluqjm0jbNSmTwMiAoOu6EkKanGmmTmqSCb2_GEXHn5gQO3_8f8iF0QPApwaQ6e0xD5AUv62MhTjApqirHG2j7dz1DOyG8YYw5Z8UWmhHMOC9pvY2eF9aqCJmybXbRqjGaD8gWwzBZyB4gjM4GCNnc5W4EvwKjy-69i6BjNlcx9in6oowNMVu-gunBG5XK7NSrqPbQZqf6APs_7y56urpczm_y27vrxfziNtdM0JiLCtI3qOoo7rqGVU2tCywYLbSgQnVatEpzWmrCeVMzokusdVeUZUNx2-lasV10tO4dvXufIEQ5mKCh75UFNwVZpR5eUPYvSDgjpCpXYLkGtXcheOjk6M2g_KckWK6cy2_nciVXCiG_nUuccoc_B6ZmgPZPai08AedrAJKPDwNeBm3AamiNT05l68w_J74AyLWTjA</recordid><startdate>19990701</startdate><enddate>19990701</enddate><creator>Preston, P.M.</creator><creator>Hall, F.R.</creator><creator>Glass, E.J.</creator><creator>Campbell, J.D.M.</creator><creator>Darghouth, M.A.</creator><creator>Ahmed, J.S.</creator><creator>Shiels, B.R.</creator><creator>Spooner, R.L.</creator><creator>Jongejan, F.</creator><creator>Brown, C.G.D.</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>19990701</creationdate><title>Innate and Adaptive Immune Responses Co-operate to Protect Cattle against Theileria annulata</title><author>Preston, P.M. ; Hall, F.R. ; Glass, E.J. ; Campbell, J.D.M. ; Darghouth, M.A. ; Ahmed, J.S. ; Shiels, B.R. ; Spooner, R.L. ; Jongejan, F. ; Brown, C.G.D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c392t-96e1012af20ffb36b8c409324c929afc9dac725c177b831c50ccf455b20dfc8a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adaptive responses</topic><topic>Animals</topic><topic>Antigens, Protozoan - immunology</topic><topic>Cattle</topic><topic>Cytokines - metabolism</topic><topic>Host-Parasite Interactions - immunology</topic><topic>Immunity</topic><topic>Innate responses</topic><topic>Leukocytes, Mononuclear - metabolism</topic><topic>Leukocytes, Mononuclear - parasitology</topic><topic>Macrophages - parasitology</topic><topic>Protective immunity</topic><topic>Protozoan Vaccines - immunology</topic><topic>Theileria annulata</topic><topic>Theileria annulata - immunology</topic><topic>Theileria annulata - physiology</topic><topic>Theileriasis - immunology</topic><topic>Vaccines, Synthetic - immunology</topic><toplevel>online_resources</toplevel><creatorcontrib>Preston, P.M.</creatorcontrib><creatorcontrib>Hall, F.R.</creatorcontrib><creatorcontrib>Glass, E.J.</creatorcontrib><creatorcontrib>Campbell, J.D.M.</creatorcontrib><creatorcontrib>Darghouth, M.A.</creatorcontrib><creatorcontrib>Ahmed, J.S.</creatorcontrib><creatorcontrib>Shiels, B.R.</creatorcontrib><creatorcontrib>Spooner, R.L.</creatorcontrib><creatorcontrib>Jongejan, F.</creatorcontrib><creatorcontrib>Brown, C.G.D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Parasitology Today</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Preston, P.M.</au><au>Hall, F.R.</au><au>Glass, E.J.</au><au>Campbell, J.D.M.</au><au>Darghouth, M.A.</au><au>Ahmed, J.S.</au><au>Shiels, B.R.</au><au>Spooner, R.L.</au><au>Jongejan, F.</au><au>Brown, C.G.D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Innate and Adaptive Immune Responses Co-operate to Protect Cattle against Theileria annulata</atitle><jtitle>Parasitology Today</jtitle><addtitle>Parasitol Today</addtitle><date>1999-07-01</date><risdate>1999</risdate><volume>15</volume><issue>7</issue><spage>268</spage><epage>274</epage><pages>268-274</pages><issn>0169-4758</issn><abstract>For many years it was assumed that Theileria annulata resembled T. parva, parasitizing lymphocytes and causing lymphoproliferative disease, with the two species being controlled by similar protective immune responses. Patricia Preston et al. here review the evidence that has led to a different view of T. annulata. It is now thought that the schizonts of T. annulata inhabit macrophages and B cells, and that tropical theileriosis is not a lymphoproliferative disease. Both innate and adaptive responses contribute to recovery from infection and resistance to challenge and cytokines produced by infected and uninfected cells influence the outcome of infection. Partial protection has been stimulated recently by defined recombinant antigens; efficacy depended upon the delivery system.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>10377528</pmid><doi>10.1016/S0169-4758(99)01466-0</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0169-4758 |
| ispartof | Parasitology Today, 1999-07, Vol.15 (7), p.268-274 |
| issn | 0169-4758 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69297423 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adaptive responses Animals Antigens, Protozoan - immunology Cattle Cytokines - metabolism Host-Parasite Interactions - immunology Immunity Innate responses Leukocytes, Mononuclear - metabolism Leukocytes, Mononuclear - parasitology Macrophages - parasitology Protective immunity Protozoan Vaccines - immunology Theileria annulata Theileria annulata - immunology Theileria annulata - physiology Theileriasis - immunology Vaccines, Synthetic - immunology |
| title | Innate and Adaptive Immune Responses Co-operate to Protect Cattle against Theileria annulata |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T08%3A42%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Innate%20and%20Adaptive%20Immune%20Responses%20Co-operate%20to%20Protect%20Cattle%20against%20Theileria%20annulata&rft.jtitle=Parasitology%20Today&rft.au=Preston,%20P.M.&rft.date=1999-07-01&rft.volume=15&rft.issue=7&rft.spage=268&rft.epage=274&rft.pages=268-274&rft.issn=0169-4758&rft_id=info:doi/10.1016/S0169-4758(99)01466-0&rft_dat=%3Cproquest_cross%3E69297423%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17311653&rft_id=info:pmid/10377528&rft_els_id=S0169475899014660&rfr_iscdi=true |