Modulation of cytokine and β-defensin 2 expressions in human gingival fibroblasts infected with Chlamydia pneumoniae

Human β-defensin 2 is an antimicrobial peptide that is produced by several epithelial cells after stimulation with micro-organisms and inflammatory mediators. Gram-negative bacteria, which are typically detected in periodontal pockets in periodontitis, elicit a stronger antibacterial peptide respons...

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Veröffentlicht in:	International immunopharmacology 2008-09, Vol.8 (9), p.1239-1247
Hauptverfasser:	Rizzo, Antonietta, Paolillo, Rossella, Buommino, Elisabetta, Lanza, Alfonso Galeota, Guida, Luigi, Annunziata, Marco, Carratelli, Caterina Romano
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult beta-Defensins - biosynthesis Biological and medical sciences Cell Proliferation Cell Survival Cells, Cultured Chlamydia Infections - metabolism Chlamydia pneumoniae Chlamydophila pneumoniae Chlamydophila pneumoniae - growth & development Chlamydophila pneumoniae - pathogenicity Cytokines Cytokines - biosynthesis Enzyme-Linked Immunosorbent Assay Fibroblasts Fibroblasts - metabolism Gingiva - cytology Gingiva - metabolism Humans Medical sciences Periodontal Diseases - metabolism Periodontal Diseases - microbiology Pharmacology. Drug treatments Proliferation Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis RNA, Messenger - genetics
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