Deoxyribonucleic acid-damaged sperm in cryopreserved-thawed specimens from cancer patients and healthy men
A similarity was found between the percentage of thawed, DNA-damaged spermatozoa in cancer patients and that in candidates to become sperm bank donors who had low sperm cryofreezability. Both groups were significantly different from the sperm bank donor group. It is suggested that the higher rate of...
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| Veröffentlicht in: | Fertility and sterility 2008-07, Vol.90 (1), p.205-208 |
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| container_title | Fertility and sterility |
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| creator | Edelstein, Avital, M.Sc Yavetz, Haim, M.D Kleiman, Sandra E., Ph.D Botchan, Amnon, M.D Hauser, Ron, M.D Paz, Gedalia, Ph.D Yogev, Leah, Ph.D |
| description | A similarity was found between the percentage of thawed, DNA-damaged spermatozoa in cancer patients and that in candidates to become sperm bank donors who had low sperm cryofreezability. Both groups were significantly different from the sperm bank donor group. It is suggested that the higher rate of DNA fragmentation in sperm from cancer patients compared with sperm bank donors is apparently a result of selecting donors by the level of sperm cryofreezability (i.e., high), rather than a direct effect of an existing malignancy. |
| doi_str_mv | 10.1016/j.fertnstert.2007.05.060 |
| format | Article |
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Obstetrics</subject><subject>Hodgkin Disease - complications</subject><subject>Hodgkin Disease - genetics</subject><subject>Hodgkin Disease - pathology</subject><subject>Humans</subject><subject>Infertility, Male - genetics</subject><subject>Infertility, Male - pathology</subject><subject>Internal Medicine</subject><subject>Lymphoma, Non-Hodgkin - complications</subject><subject>Lymphoma, Non-Hodgkin - genetics</subject><subject>Lymphoma, Non-Hodgkin - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Obstetrics and Gynecology</subject><subject>Reproductive Techniques, Assisted</subject><subject>Semen Preservation</subject><subject>Sperm Banks</subject><subject>Sperm Motility</subject><subject>Spermatozoa - pathology</subject><subject>Testicular Neoplasms - complications</subject><subject>Testicular Neoplasms - genetics</subject><subject>Testicular Neoplasms - pathology</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNksFu1DAQhiMEotvCKyBf4JYwdmInuSBBgYJUiQNwtpzxhHVInMVOWvL2eLUrKnHi4jn4-2dGnybLGIeCA1evh6KnsPi4pLcQAHUBsgAFj7Idl1LlUsnycbYD4DIH0YiL7DLGAQAUr8XT7ILXSjZSNLtseE_z7y24bvYrjuSQGXQ2t2YyP8iyeKAwMecZhm0-BIoU7sjmy97cn37RTeQj68M8MTQeKbCDWRz5JTLjLduTGZf9xhL1LHvSmzHS83O9yr5__PDt-lN---Xm8_Xb2xwl1Ete8w6aynQWsFGS-t7WWKm2k1CRak3ZtYqIi4YTEFYG0WJfGZDQllL2XVdeZa9OfQ9h_rVSXPTkItI4Gk_zGrVqU1iJJoHNCcQwxxio14fgJhM2zUEfPetBP3jWR88apE6eU_TFecbaTWQfgmexCXh5BkxEM_YhuXHxLyfSvqKuq8S9O3GUjNw5CjpisodkXSBctJ3d_2zz5p8mODrv0tyftFEc5jX4ZFxzHYUG_fV4F8ezgBq4KEtR_gFGg7kJ</recordid><startdate>20080701</startdate><enddate>20080701</enddate><creator>Edelstein, Avital, M.Sc</creator><creator>Yavetz, Haim, M.D</creator><creator>Kleiman, Sandra E., Ph.D</creator><creator>Botchan, Amnon, M.D</creator><creator>Hauser, Ron, M.D</creator><creator>Paz, Gedalia, Ph.D</creator><creator>Yogev, Leah, Ph.D</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20080701</creationdate><title>Deoxyribonucleic acid-damaged sperm in cryopreserved-thawed specimens from cancer patients and healthy men</title><author>Edelstein, Avital, M.Sc ; Yavetz, Haim, M.D ; Kleiman, Sandra E., Ph.D ; Botchan, Amnon, M.D ; Hauser, Ron, M.D ; Paz, Gedalia, Ph.D ; Yogev, Leah, Ph.D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c507t-71b084abd0c865effd7c469b504e69a3b96ee1281e0ec4accdcf4a0509355fbb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Cell Survival</topic><topic>Centrifugation, Density Gradient</topic><topic>Cryopreservation</topic><topic>DNA Damage</topic><topic>Gynecology. 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| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Biological and medical sciences Case-Control Studies Cell Survival Centrifugation, Density Gradient Cryopreservation DNA Damage Gynecology. Andrology. Obstetrics Hodgkin Disease - complications Hodgkin Disease - genetics Hodgkin Disease - pathology Humans Infertility, Male - genetics Infertility, Male - pathology Internal Medicine Lymphoma, Non-Hodgkin - complications Lymphoma, Non-Hodgkin - genetics Lymphoma, Non-Hodgkin - pathology Male Medical sciences Obstetrics and Gynecology Reproductive Techniques, Assisted Semen Preservation Sperm Banks Sperm Motility Spermatozoa - pathology Testicular Neoplasms - complications Testicular Neoplasms - genetics Testicular Neoplasms - pathology |
| title | Deoxyribonucleic acid-damaged sperm in cryopreserved-thawed specimens from cancer patients and healthy men |
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