Interphase Fluorescence In Situ Hybridization Overcomes Pitfalls of G-Banding Analysis with Special Reference to Underestimation of Chromosomal Aberration Rates

Fluorescence in situ hybridization (FISH) is suitable for detecting different types of chromosome aberrations on interphase nuclei even in specimens with no or few chromosome metaphases. However, it is not known why FISH is superior to conventional G-banding analysis. The sensitivity of interphase F...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1999-11, Vol.115 (1), p.32-38
Hauptverfasser:	Tanaka, Kimio, Arif, Mansyur, Eguchi, Mariko, Shintani, Takahiro, Kumaravel, Tirukalikundram S., Asaoku, Hiroki, Kyo, Taichi, Dohy, Hiroo, Kamada, Nanao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosome Aberrations Chromosome Banding - methods Gene Deletion Humans In Situ Hybridization, Fluorescence - methods Interphase Investigative techniques, diagnostic techniques (general aspects) Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Myeloid, Acute - genetics Medical sciences Metaphase Miscellaneous. Technology Monosomy Myelodysplastic Syndromes - genetics Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Translocation, Genetic Trisomy
Online-Zugang:	Volltext
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