Hydroxyurea as an Alternative to Blood Transfusions for the Prevention of Recurrent Stroke in Children With Sickle Cell Disease

Children with sickle cell disease (SCD) and stroke receive chronic transfusions to prevent stroke recurrence. Transfusion risks including infection, erythrocyte allosensitization, and iron overload suggest a need for alternative therapies. We previously used hydroxyurea (HU) and phlebotomy in two yo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Blood 1999-11, Vol.94 (9), p.3022-3026
Hauptverfasser:	Ware, Russell E., Zimmerman, Sherri A., Schultz, William H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Anemia, Sickle Cell - complications Anemias. Hemoglobinopathies Antisickling Agents - administration & dosage Biological and medical sciences Blood Transfusion Blood. Blood coagulation. Reticuloendothelial system Child Child, Preschool Diseases of red blood cells Hematologic and hematopoietic diseases Humans Hydroxyurea - administration & dosage Infant Medical sciences Pharmacology. Drug treatments Prospective Studies Stroke - etiology Stroke - prevention & control Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!