Functioning and nonfunctioning thyroid adenomas involve different molecular pathogenetic mechanisms

The molecular biology of follicular cell growth in thyroid nodules is still poorly understood. Because gain-of-function (activating) mutations of the thyroid-stimulating hormone receptor (TShR) and/or Gs alpha genes may confer TSh-independent growth advantage to neoplastic thyroid cells, we searched...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The journal of clinical endocrinology and metabolism 1999-11, Vol.84 (11), p.4155-4158
Hauptverfasser:	TONACCHERA, M, VITTI, P, PINCHERA, A, CHIOVATO, L, AGRETTI, P, CECCARINI, G, PERRI, A, CAVALIERE, R, MAZZI, B, NACCARATO, A. G, VIACAVA, P, MICCOLI, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - genetics Adenoma - pathology Adenoma - physiopathology Adolescent Adult Biological and medical sciences Codon Endocrinopathies Exons Female GTP-Binding Protein alpha Subunits, Gs - genetics Humans Male Medical sciences Middle Aged Mutation Non tumoral diseases. Target tissue resistance. Benign neoplasms Receptors, Thyrotropin - genetics Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Thyroid Neoplasms - physiopathology Thyroid. Thyroid axis (diseases)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!