Regulation of Cardiac Myocyte Protein Turnover and Myofibrillar Structure In Vitro by Specific Directions of Stretch

We have examined how different degrees (0.5%, 1.0%, 2.5%, 5.0%, and 10.0%) and directions of stretch regulate the turnover and accumulation of contractile proteins in cultured neonatal cardiac myocytes (NCMs). In pulse-chase experiments, stellate-shaped NCMs with random arrays of myofibrils (MFs) ex...

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Veröffentlicht in:	Circulation research 1999-11, Vol.85 (10), p.e59-e59
Hauptverfasser:	Simpson, D G, Majeski, M, Borg, T K, Terracio, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Animals Animals, Newborn Cell Size Cells, Cultured Muscle Contraction Myocardium - cytology Myocardium - metabolism Myocardium - ultrastructure Myofibrils - metabolism Myofibrils - physiology Myofibrils - ultrastructure Myosin Heavy Chains - metabolism Rats Space life sciences Stress, Mechanical
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