Screening for 21-hydroxylase–deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study

Objective: To prospectively establish the specificity, sensitivity, and positive predictive value (PPV) of a basal 17-hydroxyprogesterone (17-HP) level for the screening of 21-hydroxylase–deficient nonclassic adrenal hyperplasia (NCAH) among hyperandrogenic women. Design: Prospective observational t...

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Veröffentlicht in:	Fertility and sterility 1999-11, Vol.72 (5), p.915-925
Hauptverfasser:	Azziz, Ricardo, Hincapie, Luis A, Knochenhauer, Eric S, Dewailly, Didier, Fox, Liesl, Boots, Larry R
Format:	Artikel
Sprache:	eng
Schlagworte:	17-alpha-Hydroxyprogesterone - metabolism 21-hydroxylase Adrenal Adrenal Glands - enzymology adrenal hyperplasia Adrenal Hyperplasia, Congenital - enzymology Adrenals. Adrenal axis. Renin-angiotensin system (diseases) androgens Basal Metabolism Biological and medical sciences Case-Control Studies Endocrinopathies Female hirsutism Humans Mass Screening - methods Medical sciences Non tumoral diseases. Target tissue resistance. Benign neoplasms Predictive Value of Tests Prospective Studies Sensitivity and Specificity
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